Salivary

Background and objective: Asthma patients can be effectively treated and controlled with currently available medications, inhaled ß2-agonists and corticosteroids have harmful effects on dentition. Therefore we aimed to investigate the influence of exposure to inhaled ß2-agonists and corticosteroids...

Full description

Bibliographic Details
Main Authors: Mohie Aldeen Abd Alzaher Khalifa, Hassan Mohamed Abouelkheir, Shaban El-Fadly Khodiar, Gamal Aldeen M. Mohamed
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-10-01
Series:Egyptian Journal of Chest Disease and Tuberculosis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S042276381400106X
id doaj-2f3fa5d560e84da8b878ab95d91d8610
record_format Article
spelling doaj-2f3fa5d560e84da8b878ab95d91d86102020-11-25T00:23:18ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382014-10-0163477778810.1016/j.ejcdt.2014.05.003SalivaryMohie Aldeen Abd Alzaher Khalifa0Hassan Mohamed Abouelkheir1Shaban El-Fadly Khodiar2Gamal Aldeen M. Mohamed3Chest Department GOTHI, Mataria Teaching Hospital, Cairo, EgyptOMFS & Diagnostic Sciences Dept., Riyadh Colleges of Dentistry and Pharmacy, P.O. Box: 84891, Riyadh 11681, Saudi ArabiaClinical Pathology, Alborg Laboratory, Almadinah Almunawwarah Branch, Saudi ArabiaCommunity and Family Medicine Department, College of Medical, Taibah University, Almadinah Almunawwarah, Saudi ArabiaBackground and objective: Asthma patients can be effectively treated and controlled with currently available medications, inhaled ß2-agonists and corticosteroids have harmful effects on dentition. Therefore we aimed to investigate the influence of exposure to inhaled ß2-agonists and corticosteroids on the composition of saliva as a risk factor to increase the incidence of dental caries among children aged 8–14 years old. The study group is compared with a control group of healthy children of the same age group. Patient and methods: In a triple-blind analytical case–control study, children were selected according to inclusion criteria, divided into asthmatic group1 (n = 60), who were controlled by ß2-agonists and corticosteroids for at least six months. Control group (group II) was first-degree relatives (n = 60) matched for age. DMFS and DMFT index scores were recorded in both groups. Saliva samples were collected from each child for testing electrolytes, pH, and cariogenic bacteria. Results: The results showed higher prevalence of caries among asthmatics (group I) than controls (group II). As well as a positive correlation between, duration of asthma and the caries indices, Streptococcus mutans, Lactobacilli colonies bacteria count in asthmatic were higher than in controls. Salivary electrolytes were significantly elevated in asthmatics with caries. Conclusion: Prevalence of dental caries was higher in asthmatics than controls. High caries incidence in asthmatics related to salivary acidic pH, increase S. mutans, Lactobacilli count and medication. There is a need to create awareness among dental practitioners and pulmonologists regarding the increased caries risk in asthmatics.http://www.sciencedirect.com/science/article/pii/S042276381400106XAsthmaChildrenDental cariesSalivary electrolytesCariogenic bacteria
collection DOAJ
language English
format Article
sources DOAJ
author Mohie Aldeen Abd Alzaher Khalifa
Hassan Mohamed Abouelkheir
Shaban El-Fadly Khodiar
Gamal Aldeen M. Mohamed
spellingShingle Mohie Aldeen Abd Alzaher Khalifa
Hassan Mohamed Abouelkheir
Shaban El-Fadly Khodiar
Gamal Aldeen M. Mohamed
Salivary
Egyptian Journal of Chest Disease and Tuberculosis
Asthma
Children
Dental caries
Salivary electrolytes
Cariogenic bacteria
author_facet Mohie Aldeen Abd Alzaher Khalifa
Hassan Mohamed Abouelkheir
Shaban El-Fadly Khodiar
Gamal Aldeen M. Mohamed
author_sort Mohie Aldeen Abd Alzaher Khalifa
title Salivary
title_short Salivary
title_full Salivary
title_fullStr Salivary
title_full_unstemmed Salivary
title_sort salivary
publisher Wolters Kluwer Medknow Publications
series Egyptian Journal of Chest Disease and Tuberculosis
issn 0422-7638
publishDate 2014-10-01
description Background and objective: Asthma patients can be effectively treated and controlled with currently available medications, inhaled ß2-agonists and corticosteroids have harmful effects on dentition. Therefore we aimed to investigate the influence of exposure to inhaled ß2-agonists and corticosteroids on the composition of saliva as a risk factor to increase the incidence of dental caries among children aged 8–14 years old. The study group is compared with a control group of healthy children of the same age group. Patient and methods: In a triple-blind analytical case–control study, children were selected according to inclusion criteria, divided into asthmatic group1 (n = 60), who were controlled by ß2-agonists and corticosteroids for at least six months. Control group (group II) was first-degree relatives (n = 60) matched for age. DMFS and DMFT index scores were recorded in both groups. Saliva samples were collected from each child for testing electrolytes, pH, and cariogenic bacteria. Results: The results showed higher prevalence of caries among asthmatics (group I) than controls (group II). As well as a positive correlation between, duration of asthma and the caries indices, Streptococcus mutans, Lactobacilli colonies bacteria count in asthmatic were higher than in controls. Salivary electrolytes were significantly elevated in asthmatics with caries. Conclusion: Prevalence of dental caries was higher in asthmatics than controls. High caries incidence in asthmatics related to salivary acidic pH, increase S. mutans, Lactobacilli count and medication. There is a need to create awareness among dental practitioners and pulmonologists regarding the increased caries risk in asthmatics.
topic Asthma
Children
Dental caries
Salivary electrolytes
Cariogenic bacteria
url http://www.sciencedirect.com/science/article/pii/S042276381400106X
work_keys_str_mv AT mohiealdeenabdalzaherkhalifa salivary
AT hassanmohamedabouelkheir salivary
AT shabanelfadlykhodiar salivary
AT gamalaldeenmmohamed salivary
_version_ 1725357777447026688