Akt1 genetic variants confer increased susceptibility to thyroid cancer
The PI3K-Akt-mTOR pathway plays a central role in the development of non-medullary thyroid carcinoma (NMTC). Although somatic mutations have been identified in these genes in NMTC patients, the role of germline variants has not been investigated. Here, we selected frequently occurring genetic varian...
Main Authors: | Thomas Crezee, Mirela Petrulea, Doina Piciu, Martin Jaeger, Jan W A Smit, Theo S Plantinga, Carmen E Georgescu, Romana Netea-Maier |
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Format: | Article |
Language: | English |
Published: |
Bioscientifica
2020-12-01
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Series: | Endocrine Connections |
Subjects: | |
Online Access: | https://ec.bioscientifica.com/view/journals/ec/9/11/EC-20-0311.xml |
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