Resistance patterns of Escherichia coli causing urinary tract infection
Background: Urinary tract infection (UTI) is one of the most prevalent infectious diseases and Escherichia coli is its common cause. The aim of this study was to assess the resistance patterns of E.coli in urinary tract infections and to determine the susceptibility of E.coli to commonly used antimi...
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doaj-2f4ecbee28a041a4ae5d315b4c3511a62020-11-24T21:10:33ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722015-07-0163148151Resistance patterns of Escherichia coli causing urinary tract infectionElaheh Ferdosi-Shahandashti0Mostafa Javanian1Masoomeh Moradian-Kouchakssaraei2Babak Yeganeh3Ali Bijani4Elahe Motevaseli5Fatemeh Moradiyan-Kouchakssaraei6 Tehran University of Medical Sciences Babol University of Medical Sciences Department of Microbiology, Babol University of Medical Sciences, Babol, Iran Department of Infectious Dideases, Babol University of Medical Sciences, Babol, Iran Social Determinants of Health (SDH) Research Center, Babol University of Medical Sciences, Babol, Iran Tehran University of Medical Sciences Babol University of Medical Sciences Background: Urinary tract infection (UTI) is one of the most prevalent infectious diseases and Escherichia coli is its common cause. The aim of this study was to assess the resistance patterns of E.coli in urinary tract infections and to determine the susceptibility of E.coli to commonly used antimicrobials and also to evaluate the options for empirical treatment of UTI. Methods: This study was conducted in the Ayatollah Rouhani Teaching Hospital of Babol Medical Sciences University in North of Iran. Between January of 2013 to December 2013, antimicrobial susceptibility tests were done by disk diffusion and microdilution method. Growth of >=105 cfu/ml was considered as positive urine test. Ten commonly used antibiotics were examined for susceptibility test. Data and the results were collected and analyzed. Results: E.coli grew in 57 urine samples. Imipenem, ofloxacin, ciprofloxacin were the most sensitive antibiotics at 87.7%, 87.7% and 78.9% respectively. Whereas, cotrimoxazole, cefexime, cefotaxcime and ceftriaxone were the most resistant antibiotics. Antibiotic sensitivity of disk diffusion compared minimum inhibitory concentration (MIC) detected by microdilution had the sensitivity, specificity, positive predictive value and negative predictive value of 82%, 98%, 99% and 74%, respectively. Conclusion: Imipenem, ofloxacin and ciprofloxacin should be used in empirical therapy of UTI.http://caspjim.com/browse.php?a_code=A-10-131-1&slc_lang=en&sid=1Urinary Tract Infection UTI Escherichia coli antibiotic susceptibility antibiotic resistance disk diffusion micro dilution |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Elaheh Ferdosi-Shahandashti Mostafa Javanian Masoomeh Moradian-Kouchakssaraei Babak Yeganeh Ali Bijani Elahe Motevaseli Fatemeh Moradiyan-Kouchakssaraei |
spellingShingle |
Elaheh Ferdosi-Shahandashti Mostafa Javanian Masoomeh Moradian-Kouchakssaraei Babak Yeganeh Ali Bijani Elahe Motevaseli Fatemeh Moradiyan-Kouchakssaraei Resistance patterns of Escherichia coli causing urinary tract infection Caspian Journal of Internal Medicine Urinary Tract Infection UTI Escherichia coli antibiotic susceptibility antibiotic resistance disk diffusion micro dilution |
author_facet |
Elaheh Ferdosi-Shahandashti Mostafa Javanian Masoomeh Moradian-Kouchakssaraei Babak Yeganeh Ali Bijani Elahe Motevaseli Fatemeh Moradiyan-Kouchakssaraei |
author_sort |
Elaheh Ferdosi-Shahandashti |
title |
Resistance patterns of Escherichia coli causing urinary tract infection |
title_short |
Resistance patterns of Escherichia coli causing urinary tract infection |
title_full |
Resistance patterns of Escherichia coli causing urinary tract infection |
title_fullStr |
Resistance patterns of Escherichia coli causing urinary tract infection |
title_full_unstemmed |
Resistance patterns of Escherichia coli causing urinary tract infection |
title_sort |
resistance patterns of escherichia coli causing urinary tract infection |
publisher |
Babol University of Medical Sciences |
series |
Caspian Journal of Internal Medicine |
issn |
2008-6164 2008-6172 |
publishDate |
2015-07-01 |
description |
Background: Urinary tract infection (UTI) is one of the most prevalent
infectious diseases and Escherichia coli is its common cause. The aim of this
study was to assess the resistance patterns of E.coli in urinary tract
infections and to determine the susceptibility of E.coli to commonly used
antimicrobials and also to evaluate the options for empirical treatment of UTI. Methods: This study was conducted in the Ayatollah Rouhani
Teaching Hospital of Babol Medical Sciences University in North of Iran. Between
January of 2013 to December 2013, antimicrobial susceptibility tests were done
by disk diffusion and microdilution method. Growth of >=105
cfu/ml was considered as positive urine test. Ten commonly used antibiotics were
examined for susceptibility test. Data and the results were collected and
analyzed. Results: E.coli grew in 57 urine samples. Imipenem, ofloxacin,
ciprofloxacin were the most sensitive antibiotics at 87.7%, 87.7% and 78.9%
respectively. Whereas, cotrimoxazole, cefexime, cefotaxcime and ceftriaxone
were the most resistant antibiotics. Antibiotic sensitivity of disk diffusion
compared minimum inhibitory concentration (MIC) detected by microdilution had the
sensitivity, specificity, positive predictive value and negative predictive
value of 82%, 98%, 99% and 74%, respectively. Conclusion: Imipenem, ofloxacin and ciprofloxacin should be used
in empirical therapy of UTI. |
topic |
Urinary Tract Infection UTI Escherichia coli antibiotic susceptibility antibiotic resistance disk diffusion micro dilution |
url |
http://caspjim.com/browse.php?a_code=A-10-131-1&slc_lang=en&sid=1 |
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