Interplay of Opposing Effects of the WNT/β-Catenin Pathway and PPARγ and Implications for SARS-CoV2 Treatment

Interplay of Opposing Effects of the WNT/β-Catenin Pathway and PPARγ and Implications for SARS-CoV2 Treatment

The Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has quickly reached pandemic proportions. Cytokine profiles observed in COVID-19 patients have revealed increased levels of IL-1β, IL-2, IL-6, and TNF-α and increase...

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Bibliographic Details
Main Authors: Alexandre Vallée, Yves Lecarpentier, Jean-Noël Vallée
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
COVID-19
WNT/β-catenin pathway
PPARγ
ACE2
cytokine storm
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.666693/full

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