Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review
Periodontal disease can be treated in several ways. This paper reviewed whether antimicrobial photodynamic therapy (aPDT) in addition to scaling and root planing (SRP) produces improved clinical results over systemic antibiotics (ABs) in conjunction with SRP in adults with periodontitis. Studies wer...
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doaj-2f6427ac0a42492eb2f2be37c65868922020-11-25T02:12:18ZengMDPI AGDentistry Journal2304-67672019-11-017410810.3390/dj7040108dj7040108Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic ReviewAnimesh Pal0Sanjeev Paul1Rachel Perry2James Puryer3Bristol Dental School, Lower Maudlin Street, Bristol BS1 2LY, UKBristol Dental School, Lower Maudlin Street, Bristol BS1 2LY, UKUniversity Hospitals Bristol Research and Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UKBristol Dental School, Lower Maudlin Street, Bristol BS1 2LY, UKPeriodontal disease can be treated in several ways. This paper reviewed whether antimicrobial photodynamic therapy (aPDT) in addition to scaling and root planing (SRP) produces improved clinical results over systemic antibiotics (ABs) in conjunction with SRP in adults with periodontitis. Studies were searched using the following electronic databases: MEDLINE, the Cochrane Database of Systematic Reviews, and the Web of Science Core Collection up to and including November 2018. Four randomized controlled trials (RCTs) were reviewed to maximise the reliability of the evidence. All participants suffered from either chronic or aggressive periodontitis and each study contained SRP as an adjunct to ABs or aPDT. To determine whether groups showed improvement after treatment, the outcome parameters chosen were probing depth (PD), clinical attachment level (CAL), and bleeding on probing (BOP). Despite finding significant improvements in all groups, the differences among groups were not consistently statistically significant. The lack of homogeneity in the results among these studies indicates that it was not possible to determine a conclusion about whether aPDT or AB as an adjunct to SRP provides better improvements in periodontitis as measured by PD, CAL, and BOP. Further studies with more similar study designs are required before firm conclusions can be deduced.https://www.mdpi.com/2304-6767/7/4/108periodontitisscalingphotodynamictherapyantibioticsoutcome |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Animesh Pal Sanjeev Paul Rachel Perry James Puryer |
spellingShingle |
Animesh Pal Sanjeev Paul Rachel Perry James Puryer Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review Dentistry Journal periodontitis scaling photodynamic therapy antibiotics outcome |
author_facet |
Animesh Pal Sanjeev Paul Rachel Perry James Puryer |
author_sort |
Animesh Pal |
title |
Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review |
title_short |
Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review |
title_full |
Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review |
title_fullStr |
Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review |
title_full_unstemmed |
Is the Use of Antimicrobial Photodynamic Therapy or Systemic Antibiotics More Effective in Improving Periodontal Health When Used in Conjunction with Localised Non-Surgical Periodontal Therapy? A Systematic Review |
title_sort |
is the use of antimicrobial photodynamic therapy or systemic antibiotics more effective in improving periodontal health when used in conjunction with localised non-surgical periodontal therapy? a systematic review |
publisher |
MDPI AG |
series |
Dentistry Journal |
issn |
2304-6767 |
publishDate |
2019-11-01 |
description |
Periodontal disease can be treated in several ways. This paper reviewed whether antimicrobial photodynamic therapy (aPDT) in addition to scaling and root planing (SRP) produces improved clinical results over systemic antibiotics (ABs) in conjunction with SRP in adults with periodontitis. Studies were searched using the following electronic databases: MEDLINE, the Cochrane Database of Systematic Reviews, and the Web of Science Core Collection up to and including November 2018. Four randomized controlled trials (RCTs) were reviewed to maximise the reliability of the evidence. All participants suffered from either chronic or aggressive periodontitis and each study contained SRP as an adjunct to ABs or aPDT. To determine whether groups showed improvement after treatment, the outcome parameters chosen were probing depth (PD), clinical attachment level (CAL), and bleeding on probing (BOP). Despite finding significant improvements in all groups, the differences among groups were not consistently statistically significant. The lack of homogeneity in the results among these studies indicates that it was not possible to determine a conclusion about whether aPDT or AB as an adjunct to SRP provides better improvements in periodontitis as measured by PD, CAL, and BOP. Further studies with more similar study designs are required before firm conclusions can be deduced. |
topic |
periodontitis scaling photodynamic therapy antibiotics outcome |
url |
https://www.mdpi.com/2304-6767/7/4/108 |
work_keys_str_mv |
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