Conservative treatment of complications after integrated therapy of bladder cancer

• Main Authors: A D Kaprin, S A Ivanov, S V Garmash, A V Shestakov
• Format: Article
• Language: English
• Published: Peoples’ Friendship University of Russia (RUDN University) 2011-12-01
• Series: RUDN Journal of Medicine
• Subjects: лучевая терапия; рак мочевого пузыря; озонотерапия
• Online Access: http://journals.rudn.ru/medicine/article/view/3565

Aim: to evaluate efficacy of systemic and local ozone therapy for correction of radiation complications after complex therapy of bladder cancer. Materials & methods: 25 patients with bladder cancer at the stage T2-Т3аN0M0 treated in FSI Russian Scientific Rentgenradiology Centre (from 2003 to 2008) were included in the study. The first group (12 patients) for the treatment of late complications received complex therapy for 3 months, the second group (13 patients) - standard symptomatic therapy. Results: the control study in 12 months showed a significant decline of total score of IPSS and QoL in the first group in comparison with the second one (17.5 ± 5.2 vs 23.5 ± 6 and 3.1 ± 1.1 vs 3.8 ± 1.5, respectively). Conclusions: for prevention and correction of radiotherapy complications of bladder cancer it is necessary to use additional methods of treatment including ozone therapy and pharmacotherapy which permit to improve the quality of patient's life.