Investigation of growth stimulating activity of 2-heteryl-[1,2,4]triazolo [1,5-c]quinazolines and products of its nucleophilic degradation

Nucleophilic degradation of 2-heteryl-[1,2,4]triazolo[1,5-c]quinazolines was investigated and the structure of {2-(3-heteryl)-1H-1,2,4-triazol-5-yl]phenyl}ami­nes was unequivocally proved by spectral methods. Growth stimulating activity of these compounds was investigated and it was found that the m...

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Bibliographic Details
Main Authors: A. K. Bilyi, S. I. Kovalenko, O. V. Prihodko
Format: Article
Language:English
Published: Zaporozhye State Medical University 2013-02-01
Series:Zaporožskij Medicinskij Žurnal
Subjects:
Online Access:http://zmj.zsmu.edu.ua/article/view/15606/13406
Description
Summary:Nucleophilic degradation of 2-heteryl-[1,2,4]triazolo[1,5-c]quinazolines was investigated and the structure of {2-(3-heteryl)-1H-1,2,4-triazol-5-yl]phenyl}ami­nes was unequivocally proved by spectral methods. Growth stimulating activity of these compounds was investigated and it was found that the most pronounced growth stimulating activity 2.5 and 2.7 compounds showed among studied ones. They contain benzofuran and indole radicals correspondingly in position 2 of triazole ring.
ISSN:2306-4145
2310-1210