Placental amniotic epithelial cells and their therapeutic potential in liver diseases

As a unique source of stem cells, there is a growing interest in amniotic epithelial (AE) cells. Placenta is readily available; in fact, it is often discarded following delivery. As such, it is without the ethical concerns of embryonic stem cells. Further advantages to AE include that AE cells do no...

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Bibliographic Details
Main Authors: Asli eTahan, Veysel eTahan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2014.00048/full
Description
Summary:As a unique source of stem cells, there is a growing interest in amniotic epithelial (AE) cells. Placenta is readily available; in fact, it is often discarded following delivery. As such, it is without the ethical concerns of embryonic stem cells. Further advantages to AE include that AE cells do not demonstrate tumorigenicity upon transplantation, and are gifted with immunomodulatory and anti-inflamatory properties. Thus, AE cells have exceptional features for use as cell-based therapies for liver disease.
ISSN:2296-858X