Identification of continuous human B-cell epitopes in the VP35, VP40, nucleoprotein and glycoprotein of Ebola virus.
Ebola virus (EBOV) is a highly virulent human pathogen. Recovery of infected patients is associated with efficient EBOV-specific immunoglobulin G (IgG) responses, whereas fatal outcome is associated with defective humoral immunity. As B-cell epitopes on EBOV are poorly defined, we sought to identify...
Main Authors: | Pierre Becquart, Tanel Mahlakõiv, Dieudonné Nkoghe, Eric M Leroy |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4051576?pdf=render |
Similar Items
-
Assembly of the Ebola Virus Nucleoprotein from a Chaperoned VP35 Complex
by: Robert N. Kirchdoerfer, et al.
Published: (2015-07-01) -
Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology
by: Harty Ronald N, et al.
Published: (2006-05-01) -
Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis
by: Wei Xu, et al.
Published: (2017-06-01) -
Integrated Computational Approach for Virtual Hit Identification against Ebola Viral Proteins VP35 and VP40
by: Muhammad Usman Mirza, et al.
Published: (2016-10-01) -
An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions
by: Daisy W. Leung, et al.
Published: (2015-04-01)