Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy

Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy

As a new antioxidant, nanoceria is of significant importance in applications of medical and biological fields. In comparison with conventional organic antioxidants, nanoceria has multienzyme mimetic activity by Ce4+/Ce3+ redox cycle. This unique regenerative/autocatalytic property has been widely us...

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Main Authors: Changyan Li, Xiangcheng Shi, Qiudi Shen, Chen Guo, Zepeng Hou, Jun Zhang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2018/4857461
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spelling doaj-2fa0d276f7424f489f21d14141d36bd12020-11-24T22:38:09ZengHindawi LimitedJournal of Nanomaterials1687-41101687-41292018-01-01201810.1155/2018/48574614857461Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant TherapyChangyan Li0Xiangcheng Shi1Qiudi Shen2Chen Guo3Zepeng Hou4Jun Zhang5College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, ChinaCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, ChinaCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, ChinaCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, ChinaCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, ChinaCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, ChinaAs a new antioxidant, nanoceria is of significant importance in applications of medical and biological fields. In comparison with conventional organic antioxidants, nanoceria has multienzyme mimetic activity by Ce4+/Ce3+ redox cycle. This unique regenerative/autocatalytic property has been widely used in the aspects of free-radical scavenger, radiation protection, oxidative-stress-related disease, drug delivery, biosensor, tissue engineering, cancer biomarker, and anti-inflammatory. This paper reviews the latest breakthrough of nanoceria as an antioxidant in applications of medical and biological fields on the base of the authors’ research works on resistance to oxidation and cytotoxicity. The challenges of nanoceria encountered in applications in medical and biological fields are commented as well.http://dx.doi.org/10.1155/2018/4857461
collection DOAJ
language English
format Article
sources DOAJ
author Changyan Li
Xiangcheng Shi
Qiudi Shen
Chen Guo
Zepeng Hou
Jun Zhang
spellingShingle Changyan Li
Xiangcheng Shi
Qiudi Shen
Chen Guo
Zepeng Hou
Jun Zhang
Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy
Journal of Nanomaterials
author_facet Changyan Li
Xiangcheng Shi
Qiudi Shen
Chen Guo
Zepeng Hou
Jun Zhang
author_sort Changyan Li
title Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy
title_short Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy
title_full Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy
title_fullStr Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy
title_full_unstemmed Hot Topics and Challenges of Regenerative Nanoceria in Application of Antioxidant Therapy
title_sort hot topics and challenges of regenerative nanoceria in application of antioxidant therapy
publisher Hindawi Limited
series Journal of Nanomaterials
issn 1687-4110
1687-4129
publishDate 2018-01-01
description As a new antioxidant, nanoceria is of significant importance in applications of medical and biological fields. In comparison with conventional organic antioxidants, nanoceria has multienzyme mimetic activity by Ce4+/Ce3+ redox cycle. This unique regenerative/autocatalytic property has been widely used in the aspects of free-radical scavenger, radiation protection, oxidative-stress-related disease, drug delivery, biosensor, tissue engineering, cancer biomarker, and anti-inflammatory. This paper reviews the latest breakthrough of nanoceria as an antioxidant in applications of medical and biological fields on the base of the authors’ research works on resistance to oxidation and cytotoxicity. The challenges of nanoceria encountered in applications in medical and biological fields are commented as well.
url http://dx.doi.org/10.1155/2018/4857461
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AT xiangchengshi hottopicsandchallengesofregenerativenanoceriainapplicationofantioxidanttherapy
AT qiudishen hottopicsandchallengesofregenerativenanoceriainapplicationofantioxidanttherapy
AT chenguo hottopicsandchallengesofregenerativenanoceriainapplicationofantioxidanttherapy
AT zepenghou hottopicsandchallengesofregenerativenanoceriainapplicationofantioxidanttherapy
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