Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain.

Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain.

Chromatin environments differ greatly within a eukaryotic genome, depending on expression state, chromosomal location, and nuclear position. In genomic regions characterized by high repeat content and high gene density, chromatin structure must silence transposable elements but permit expression of...

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Bibliographic Details
Main Authors: Nicole C Riddle, Youngsook L Jung, Tingting Gu, Artyom A Alekseyenko, Dalal Asker, Hongxing Gui, Peter V Kharchenko, Aki Minoda, Annette Plachetka, Yuri B Schwartz, Michael Y Tolstorukov, Mitzi I Kuroda, Vincenzo Pirrotta, Gary H Karpen, Peter J Park, Sarah C R Elgin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3447959?pdf=render

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