A current perspective of canstatin, a fragment of type IV collagen alpha 2 chain

Type IV collagen is a main component of basement membrane extracellular matrix. Canstatin, a non-collagenous C-terminal fragment of type IV collagen α2 chain, was firstly identified as an endogenous anti-angiogenic and anti-tumor factor, which also has an anti-lymphangiogenic effect. Then, canstatin...

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Bibliographic Details
Main Authors: Muneyoshi Okada, Hideyuki Yamawaki
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861318302202

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