A current perspective of canstatin, a fragment of type IV collagen alpha 2 chain
Type IV collagen is a main component of basement membrane extracellular matrix. Canstatin, a non-collagenous C-terminal fragment of type IV collagen α2 chain, was firstly identified as an endogenous anti-angiogenic and anti-tumor factor, which also has an anti-lymphangiogenic effect. Then, canstatin...
Main Authors: | Muneyoshi Okada, Hideyuki Yamawaki |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-02-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861318302202 |
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