INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION
The article is devoted to the study of activity of lipid peroxidation processes and their influence on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection. Activation of lipid peroxidation processes in pregnant women with cyt...
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Scientific Сentre for Family Health and Human Reproduction Problems
2014-04-01
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doaj-2fe204c912e64308875216ddbeb95d902021-08-17T13:52:50ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962014-04-010224281677INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTIONN. A. Ishutina0I. A. Andrievskaya1O. L. Kutepova2A. G. Mironenko3Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMSFar Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMSFar Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMSFar Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMSThe article is devoted to the study of activity of lipid peroxidation processes and their influence on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection. Activation of lipid peroxidation processes in pregnant women with cytomegalovirus infection determined by the contents of TBA-active products is accompanied by accumulation of cytotoxic factors - arachidonic acid (1 trimester - up by 31 %, 11 trimester - up by 68 %, 111 trimester - up by 41 %) and lysophosphatidylcholine (1 trimester - up by 85 %, 11 trimester - up by 55 %, 111 trimester - up by 13 %), causes disorders of oxygen-transport properties of hemoglobin in erythrocytes (decrease of total erythrocytes and hemoglobin count), more than double increase of indices of thermolabile hemoglobin at slight decrease of oxyhemoglobin, increase of methemoglobin (1 trimester - up by 60 %, 11 trimester - up by 25 %, 111 trimester - up by 16 %, in comparison with control), that causes decrease of transportation and delivery of oxygen to the tissues and can be the reason of hypoxia.https://www.actabiomedica.ru/jour/article/view/1731pregnancycytomegalovirus infectionlipids peroxidationhemoglobin |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
N. A. Ishutina I. A. Andrievskaya O. L. Kutepova A. G. Mironenko |
spellingShingle |
N. A. Ishutina I. A. Andrievskaya O. L. Kutepova A. G. Mironenko INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION Acta Biomedica Scientifica pregnancy cytomegalovirus infection lipids peroxidation hemoglobin |
author_facet |
N. A. Ishutina I. A. Andrievskaya O. L. Kutepova A. G. Mironenko |
author_sort |
N. A. Ishutina |
title |
INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION |
title_short |
INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION |
title_full |
INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION |
title_fullStr |
INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION |
title_full_unstemmed |
INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION |
title_sort |
influence of lipid peroxidation processes on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
series |
Acta Biomedica Scientifica |
issn |
2541-9420 2587-9596 |
publishDate |
2014-04-01 |
description |
The article is devoted to the study of activity of lipid peroxidation processes and their influence on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection. Activation of lipid peroxidation processes in pregnant women with cytomegalovirus infection determined by the contents of TBA-active products is accompanied by accumulation of cytotoxic factors - arachidonic acid (1 trimester - up by 31 %, 11 trimester - up by 68 %, 111 trimester - up by 41 %) and lysophosphatidylcholine (1 trimester - up by 85 %, 11 trimester - up by 55 %, 111 trimester - up by 13 %), causes disorders of oxygen-transport properties of hemoglobin in erythrocytes (decrease of total erythrocytes and hemoglobin count), more than double increase of indices of thermolabile hemoglobin at slight decrease of oxyhemoglobin, increase of methemoglobin (1 trimester - up by 60 %, 11 trimester - up by 25 %, 111 trimester - up by 16 %, in comparison with control), that causes decrease of transportation and delivery of oxygen to the tissues and can be the reason of hypoxia. |
topic |
pregnancy cytomegalovirus infection lipids peroxidation hemoglobin |
url |
https://www.actabiomedica.ru/jour/article/view/1731 |
work_keys_str_mv |
AT naishutina influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection AT iaandrievskaya influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection AT olkutepova influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection AT agmironenko influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection |
_version_ |
1721204632961679360 |