The efficacy of 2-nitrovinylfuran derivatives against Leishmania in vitro and in vivo

The efficacy of 2-nitrovinylfuran derivatives against Leishmania in vitro and in vivo

Despite recent advances in the treatment of some forms of leishmaniasis, the available drugs are still far from ideal due to inefficacy, parasite resistance, toxicity and cost. The wide-spectrum antimicrobial activity of 2-nitrovinylfuran compounds has been described, as has their activity against T...

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Bibliographic Details
Main Authors: Sergio Sifontes-Rodríguez, Lianet Monzote-Fidalgo, Nilo Castañedo-Cancio, Ana Margarita Montalvo-Álvarez, Yamilé López-Hernández, Niurka Mollineda Diogo, Juan Francisco Infante-Bourzac, Oliver Pérez-Martín, Alfredo Meneses-Marcel, José Antonio Escario García-Trevijano, Miguel Ángel Cabrera-Pérez
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2015-04-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
nitrovinylfuran
furvina
UC245
Leishmania
BALB/c
promastigote
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000200166&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000200166&lng=en&tlng=en

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