Oxidized LDL‐dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy

Oxidized LDL‐dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy

Abstract Arrhythmogenic cardiomyopathy (ACM) is hallmarked by ventricular fibro‐adipogenic alterations, contributing to cardiac dysfunctions and arrhythmias. Although genetically determined (e.g., PKP2 mutations), ACM phenotypes are highly variable. More data on phenotype modulators, clinical progno...

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Main Authors: Elena Sommariva, Ilaria Stadiotti, Michela Casella, Valentina Catto, Antonio Dello Russo, Corrado Carbucicchio, Lorenzo Arnaboldi, Simona De Metrio, Giuseppina Milano, Alessandro Scopece, Manuel Casaburo, Daniele Andreini, Saima Mushtaq, Edoardo Conte, Mattia Chiesa, Walter Birchmeier, Elisa Cogliati, Adolfo Paolin, Eva König, Viviana Meraviglia, Monica De Musso, Chiara Volani, Giada Cattelan, Werner Rauhe, Linda Turnu, Benedetta Porro, Matteo Pedrazzini, Marina Camera, Alberto Corsini, Claudio Tondo, Alessandra Rossini, Giulio Pompilio
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:EMBO Molecular Medicine
Subjects:
Arrhythmogenic Cardiomyopathy
ARVC
adipogenesis
oxidative stress
lipoproteins
Online Access:https://doi.org/10.15252/emmm.202114365

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