Effect of Luteolin and Apigenin on the Production of Il-31 and Il-33 in Lipopolysaccharides-Activated Microglia Cells and Their Mechanism of Action

Effect of Luteolin and Apigenin on the Production of Il-31 and Il-33 in Lipopolysaccharides-Activated Microglia Cells and Their Mechanism of Action

Microglia cells are resident cells of the central nervous system (CNS) charged with modulating inflammation in the CNS. Overstimulation of microglia cells continuously releases inflammatory mediators that contribute to neurodegenerative diseases. Apigenin and Luteolin are flavonoids with reported an...

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Bibliographic Details
Main Authors: Denis Nchang Che, Byoung Ok Cho, Ji-su Kim, Jae Young Shin, Hyun Ju Kang, Seon Il Jang
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nutrients
Subjects:
microglia cells
neuro-inflammation
il-31
il-33
luteolin
apigenin
Online Access:https://www.mdpi.com/2072-6643/12/3/811

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