Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA)
Abstract Background Previous studies have reported associations between hearing impairment (HI) and cognitive impairment, but the evidence is not conclusive while considering concurrent geriatric syndromes. Especially, evidence from previous studies rarely came from Asian studies. This study aimed t...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
|
Series: | BMC Geriatrics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12877-021-02012-4 |
id |
doaj-304317fcad0e430d9430df40adb1247e |
---|---|
record_format |
Article |
spelling |
doaj-304317fcad0e430d9430df40adb1247e2021-01-24T12:10:08ZengBMCBMC Geriatrics1471-23182021-01-0121111010.1186/s12877-021-02012-4Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA)Chi-Jung Tai0Tzyy-Guey Tseng1Yu-Han Hsiao2Tsu-Ann Kuo3Ching-Ya Huang4Yi-Hsin Yang5Meng-Chih Lee6Department of Family Medicine, Pingtung Hospital, Ministry of Health and WelfareDepartment of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical UniversityDepartment of Family Medicine, Taichung Hospital, Ministry of Health and WelfareDepartment of Medical Sociology and Social Work, Chung Shan Medical UniversityDepartment of Family Medicine, Pingtung Hospital, Ministry of Health and WelfareSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical UniversityDepartment of Family Medicine, Taichung Hospital, Ministry of Health and WelfareAbstract Background Previous studies have reported associations between hearing impairment (HI) and cognitive impairment, but the evidence is not conclusive while considering concurrent geriatric syndromes. Especially, evidence from previous studies rarely came from Asian studies. This study aimed to evaluate the independent effects of HI and hearing aid use on the incidence of cognitive impairment while considering most geriatric confounders. Methods This population-based, propensity-score matched cohort study used cohort from Waves IV–VII (1999–2011) survey of the Taiwan Longitudinal Study on Aging (TLSA). Cognitive impairment was identified based on Short Portable Mental Status Questionnaire (SPMSQ) scores. The hazard ratio (HR) was calculated using the Cox proportional hazard regression adjusting for age, sex, comorbidities, socioeconomic status, Center for Epidemiologic Studies Depression (CES-D) scores, the instrumental activities of daily living scale, mobility condition and quality of life. In addition, social support and participation were also considered as confounders in the analysis. To assess the robustness of our findings, we conducted a sensitivity analysis designed to access unmeasured confounding factors by calculating E-values. Results After 1:1 propensity-score matching, we included 709 participants in both the HI and non-HI groups with a mean age of 73.4 years and 39.4% of participants were female. The mean follow-up was 8.9 ± 3.9 years. The HI group had a higher incidence of cognitive impairment than the non-HI group (74.5% vs. 69.1%, respectively), with an adjusted HR of 1.16 (95% confidence interval [CI], 1.03–1.32) based on a 12-year follow up. The E-value was 1.45 for the estimate, which provided evidence for this study’s robustness. Although, a subgroup analysis showed that hearing aid use was associated with lower incidences of cognitive impairment (66.3% vs. 75.6%) when compared to non-users in the HI group, the adjusted HR of 0.82 (95% CI, 0.61–1.09) revealed no significant differences. Conclusions HI was an independent risk factor of incident cognitive impairment on top of concurrent geriatric syndromes. Early HI detection may thus be effective for preventing cognitive decline. Further studies are needed to evaluate the effect of hearing aid use on the prevention of cognitive decline.https://doi.org/10.1186/s12877-021-02012-4Cognitive impairmentFrailtyGeriatric syndromesHearing aidHearing impairment |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chi-Jung Tai Tzyy-Guey Tseng Yu-Han Hsiao Tsu-Ann Kuo Ching-Ya Huang Yi-Hsin Yang Meng-Chih Lee |
spellingShingle |
Chi-Jung Tai Tzyy-Guey Tseng Yu-Han Hsiao Tsu-Ann Kuo Ching-Ya Huang Yi-Hsin Yang Meng-Chih Lee Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA) BMC Geriatrics Cognitive impairment Frailty Geriatric syndromes Hearing aid Hearing impairment |
author_facet |
Chi-Jung Tai Tzyy-Guey Tseng Yu-Han Hsiao Tsu-Ann Kuo Ching-Ya Huang Yi-Hsin Yang Meng-Chih Lee |
author_sort |
Chi-Jung Tai |
title |
Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA) |
title_short |
Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA) |
title_full |
Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA) |
title_fullStr |
Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA) |
title_full_unstemmed |
Effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the Taiwan Longitudinal Study on Aging (TLSA) |
title_sort |
effects of hearing impairment and hearing aid use on the incidence of cognitive impairment among community-dwelling older adults: evidence from the taiwan longitudinal study on aging (tlsa) |
publisher |
BMC |
series |
BMC Geriatrics |
issn |
1471-2318 |
publishDate |
2021-01-01 |
description |
Abstract Background Previous studies have reported associations between hearing impairment (HI) and cognitive impairment, but the evidence is not conclusive while considering concurrent geriatric syndromes. Especially, evidence from previous studies rarely came from Asian studies. This study aimed to evaluate the independent effects of HI and hearing aid use on the incidence of cognitive impairment while considering most geriatric confounders. Methods This population-based, propensity-score matched cohort study used cohort from Waves IV–VII (1999–2011) survey of the Taiwan Longitudinal Study on Aging (TLSA). Cognitive impairment was identified based on Short Portable Mental Status Questionnaire (SPMSQ) scores. The hazard ratio (HR) was calculated using the Cox proportional hazard regression adjusting for age, sex, comorbidities, socioeconomic status, Center for Epidemiologic Studies Depression (CES-D) scores, the instrumental activities of daily living scale, mobility condition and quality of life. In addition, social support and participation were also considered as confounders in the analysis. To assess the robustness of our findings, we conducted a sensitivity analysis designed to access unmeasured confounding factors by calculating E-values. Results After 1:1 propensity-score matching, we included 709 participants in both the HI and non-HI groups with a mean age of 73.4 years and 39.4% of participants were female. The mean follow-up was 8.9 ± 3.9 years. The HI group had a higher incidence of cognitive impairment than the non-HI group (74.5% vs. 69.1%, respectively), with an adjusted HR of 1.16 (95% confidence interval [CI], 1.03–1.32) based on a 12-year follow up. The E-value was 1.45 for the estimate, which provided evidence for this study’s robustness. Although, a subgroup analysis showed that hearing aid use was associated with lower incidences of cognitive impairment (66.3% vs. 75.6%) when compared to non-users in the HI group, the adjusted HR of 0.82 (95% CI, 0.61–1.09) revealed no significant differences. Conclusions HI was an independent risk factor of incident cognitive impairment on top of concurrent geriatric syndromes. Early HI detection may thus be effective for preventing cognitive decline. Further studies are needed to evaluate the effect of hearing aid use on the prevention of cognitive decline. |
topic |
Cognitive impairment Frailty Geriatric syndromes Hearing aid Hearing impairment |
url |
https://doi.org/10.1186/s12877-021-02012-4 |
work_keys_str_mv |
AT chijungtai effectsofhearingimpairmentandhearingaiduseontheincidenceofcognitiveimpairmentamongcommunitydwellingolderadultsevidencefromthetaiwanlongitudinalstudyonagingtlsa AT tzyygueytseng effectsofhearingimpairmentandhearingaiduseontheincidenceofcognitiveimpairmentamongcommunitydwellingolderadultsevidencefromthetaiwanlongitudinalstudyonagingtlsa AT yuhanhsiao effectsofhearingimpairmentandhearingaiduseontheincidenceofcognitiveimpairmentamongcommunitydwellingolderadultsevidencefromthetaiwanlongitudinalstudyonagingtlsa AT tsuannkuo effectsofhearingimpairmentandhearingaiduseontheincidenceofcognitiveimpairmentamongcommunitydwellingolderadultsevidencefromthetaiwanlongitudinalstudyonagingtlsa AT chingyahuang effectsofhearingimpairmentandhearingaiduseontheincidenceofcognitiveimpairmentamongcommunitydwellingolderadultsevidencefromthetaiwanlongitudinalstudyonagingtlsa AT yihsinyang effectsofhearingimpairmentandhearingaiduseontheincidenceofcognitiveimpairmentamongcommunitydwellingolderadultsevidencefromthetaiwanlongitudinalstudyonagingtlsa AT mengchihlee effectsofhearingimpairmentandhearingaiduseontheincidenceofcognitiveimpairmentamongcommunitydwellingolderadultsevidencefromthetaiwanlongitudinalstudyonagingtlsa |
_version_ |
1724326271002869760 |