NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production.

NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production.

Trypanosoma cruzi (T. cruzi) is an intracellular protozoan parasite and the etiological agent of Chagas disease, a chronic infectious illness that affects millions of people worldwide. Although the role of TLR and Nod1 in the control of T. cruzi infection is well-established, the involvement of infl...

Full description

Bibliographic Details
Main Authors: Virginia M Gonçalves, Kely C Matteucci, Carina L Buzzo, Bruna H Miollo, Danny Ferrante, Ana C Torrecilhas, Mauricio M Rodrigues, Jose M Alvarez, Karina R Bortoluci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3789781?pdf=render

Internet

http://europepmc.org/articles/PMC3789781?pdf=render

Similar Items