Knockdown of lncRNA-H19 inhibits cell viability, migration and invasion while promotes apoptosis via microRNA-143/RUNX2 axis in retinoblastoma

Knockdown of lncRNA-H19 inhibits cell viability, migration and invasion while promotes apoptosis via microRNA-143/RUNX2 axis in retinoblastoma

Background: Even though the role of long non-coding RNA H19 (lncRNA-H19) in diverse cancer types has been studied, exact effect of lncRNA-H19 as well as the underlying mechanism in retinoblastoma (RB) is poorly reported. We aimed to explore the possible functions of lncRNA-H19 in human RB Y79 cells....

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Bibliographic Details
Main Authors: Defeng Qi, Mingming Wang, Fenghua Yu
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Retinoblastoma
lncRNA-H19
microRNA-143
RUNX2
PI3K/AKT/mTOR
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218340253

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http://www.sciencedirect.com/science/article/pii/S0753332218340253

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