Molecular and Metabolic Markers of Fructose Induced Hepatic Insulin Resistance in Developing and Adult Rats are Distinct and Aegle marmelos is an Effective Modulator

Molecular and Metabolic Markers of Fructose Induced Hepatic Insulin Resistance in Developing and Adult Rats are Distinct and Aegle marmelos is an Effective Modulator

Abstract The time course of pathogenesis of fructose mediated hepatic insulin resistance (HepIR) is not well-delineated and we chronicle it here from post-weaning to adulthood stages. Weaned rats were provided for either 4 or 8 weeks, i.e., upto adolescence or adulthood, chow + drinking water, chow ...

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Bibliographic Details
Main Authors: Jayachandran Nair, Thirumurthy Velpandian, Ujjalkumar Subhash Das, Prateek Sharma, Tapas Nag, Sandeep R. Mathur, Rajani Mathur
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Marmelos
Hepatic Insulin Resistance (HepIR)
Fructose Intake
Vascular Endothelial Growth Factor (VEGF)
Ghrelin
Online Access:https://doi.org/10.1038/s41598-018-33503-x

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