Transitional Cell Carcinoma of the Ovary
Objective: Transitional cell carcinoma (TCC) of the ovary is a rare, recently recognized, subtype of ovarian surface epithelial cancer. We present a case of TCC of the ovary, managed by staging operation and followed by postoperative chemotherapy with carboplatin and cyclophosphamide. Case Report: A...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2006-09-01
|
Series: | Taiwanese Journal of Obstetrics & Gynecology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455909602400 |
id |
doaj-306b8cb2bdc740b5ac0561a3f57ec818 |
---|---|
record_format |
Article |
spelling |
doaj-306b8cb2bdc740b5ac0561a3f57ec8182020-11-24T23:13:42ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592006-09-0145326827110.1016/S1028-4559(09)60240-0Transitional Cell Carcinoma of the OvaryChia-Hui LinFu-Shing LiuEsther Shih-Chu HoObjective: Transitional cell carcinoma (TCC) of the ovary is a rare, recently recognized, subtype of ovarian surface epithelial cancer. We present a case of TCC of the ovary, managed by staging operation and followed by postoperative chemotherapy with carboplatin and cyclophosphamide. Case Report: A 67-year-old postmenopausal woman presented with a 2-year history of progressive enlargement of an abdominal mass. Pelvic sonography and abdominal computed tomography showed a pelvic mass measuring 210 × 165 × 203 mm. The serum CA-125 titer was also elevated (65.01 U/mL). A staging operation with total abdominal hysterectomy, bilateral salpingo-oophorectomy, infracolic omentectomy and pelvic lymph node dissection was performed. After surgery, the pathologic report of the left ovarian tumor was TCC, grade 2-3, stage IA. The patient then underwent four cycles of postoperative chemotherapy with carboplatin and cyclophosphamide. CA-125 levels declined to within the normal range after the first cycle of chemotherapy. Conclusion: TCC of the ovary is a rare subtype of epithelial ovarian cancer. It differs from malignant Brenner tumor by the absence of a benign or borderline Brenner component. Surgical resection is the primary therapeutic approach, and patient outcomes after chemotherapy are better than for other types of common epithelial ovarian cancers.http://www.sciencedirect.com/science/article/pii/S1028455909602400ovarytransitional cell carcinoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chia-Hui Lin Fu-Shing Liu Esther Shih-Chu Ho |
spellingShingle |
Chia-Hui Lin Fu-Shing Liu Esther Shih-Chu Ho Transitional Cell Carcinoma of the Ovary Taiwanese Journal of Obstetrics & Gynecology ovary transitional cell carcinoma |
author_facet |
Chia-Hui Lin Fu-Shing Liu Esther Shih-Chu Ho |
author_sort |
Chia-Hui Lin |
title |
Transitional Cell Carcinoma of the Ovary |
title_short |
Transitional Cell Carcinoma of the Ovary |
title_full |
Transitional Cell Carcinoma of the Ovary |
title_fullStr |
Transitional Cell Carcinoma of the Ovary |
title_full_unstemmed |
Transitional Cell Carcinoma of the Ovary |
title_sort |
transitional cell carcinoma of the ovary |
publisher |
Elsevier |
series |
Taiwanese Journal of Obstetrics & Gynecology |
issn |
1028-4559 |
publishDate |
2006-09-01 |
description |
Objective: Transitional cell carcinoma (TCC) of the ovary is a rare, recently recognized, subtype of ovarian surface epithelial cancer. We present a case of TCC of the ovary, managed by staging operation and followed by postoperative chemotherapy with carboplatin and cyclophosphamide.
Case Report: A 67-year-old postmenopausal woman presented with a 2-year history of progressive enlargement of an abdominal mass. Pelvic sonography and abdominal computed tomography showed a pelvic mass measuring 210 × 165 × 203 mm. The serum CA-125 titer was also elevated (65.01 U/mL). A staging operation with total abdominal hysterectomy, bilateral salpingo-oophorectomy, infracolic omentectomy and pelvic lymph node dissection was performed. After surgery, the pathologic report of the left ovarian tumor was TCC, grade 2-3, stage IA. The patient then underwent four cycles of postoperative chemotherapy with carboplatin and cyclophosphamide. CA-125 levels declined to within the normal range after the first cycle of chemotherapy.
Conclusion: TCC of the ovary is a rare subtype of epithelial ovarian cancer. It differs from malignant Brenner tumor by the absence of a benign or borderline Brenner component. Surgical resection is the primary therapeutic approach, and patient outcomes after chemotherapy are better than for other types of common epithelial ovarian cancers. |
topic |
ovary transitional cell carcinoma |
url |
http://www.sciencedirect.com/science/article/pii/S1028455909602400 |
work_keys_str_mv |
AT chiahuilin transitionalcellcarcinomaoftheovary AT fushingliu transitionalcellcarcinomaoftheovary AT esthershihchuho transitionalcellcarcinomaoftheovary |
_version_ |
1725597030784434176 |