Red cell interactions with amyloid-β1–40 fibrils in a murine model

Red cell interactions with amyloid-β1–40 fibrils in a murine model

Vascular amyloidosis in Alzheimer's disease (AD) results in the exposure of red blood cells to β-amyloid fibrils (Aβ). The potential in vivo ramifications of this exposure have been investigated by injecting Aβ1–40 alone or Aβ-bound mouse red blood cells into the circulation of C57BL/6 mice. Re...

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Bibliographic Details
Main Authors: Luke B. Ravi, Suresh Poosala, Dongchoon Ahn, Francis J. Chrest, Edward L. Spangler, Rajadas Jayakumar, Enika Nagababu, Joy G. Mohanty, Mark Talan, Donald K. Ingram, Joseph M. Rifkind
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Neurobiology of Disease
Subjects:
Erythrocytes
β-Amyloid
Alzheimer's disease
Murine in vivo study
Spleen
Liver
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610400275X

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http://www.sciencedirect.com/science/article/pii/S096999610400275X

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