A dual role for KRT81: a miR-SNP associated with recurrence in non-small-cell lung cancer and a novel marker of squamous cell lung carcinoma.

MicroRNAs (miRNAs) play an important role in carcinogenesis through the regulation of their target genes. miRNA-related single nucleotide polymorphisms (miR-SNPs) can affect miRNA biogenesis and target sites and can alter microRNA expression and functions. We examined 11 miR-SNPs, including 5 in mic...

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Main Authors: Marc Campayo, Alfons Navarro, Nuria Viñolas, Rut Tejero, Carmen Muñoz, Tania Diaz, Ramon Marrades, Maria L Cabanas, Josep M Gimferrer, Pere Gascon, Jose Ramirez, Mariano Monzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3143163?pdf=render