Advances in Tumour Biomarkers for Screening, Diagnosis and Management of Ovarian Malignancies

• Main Authors: Naina Kumar, Amit Kant Singh
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2018-04-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: antibodies; cancer; chemotherapy
• Online Access: https://jcdr.net/articles/PDF/11453/34896_CE(RA1)_F(AP)_PF1(MLS_BT_SHU)_PFA(NC_BT_SL)_PB(BT_SL)_PN(SL).pdf

Ovarian cancer is one of most deadly malignancies in women, accounting for 1,52,000 deaths annually worldwide. Most ovarian malignancies are diagnosed at advanced stages when they have already metastasised to distant sites. Many researches are still under way to find means of detecting this malignancy at an early stage, so as to improve overall survival rates associated with it. One such way is use of serum biomarkers, which can help to some extent in detecting these cancers at an early stage as well as to follow-up patients during chemotherapy, after surgery and for detection of recurrent/persistent disease. Present review throws light on some of these novel biomarkers that help in detection and follow-up of women with ovarian cancers.