In mice, tuberculosis progression is associated with intensive inflammatory response and the accumulation of Gr-1 cells in the lungs.

Infection with Mycobacterium tuberculosis (Mtb) results in different clinical outcomes ranging from asymptomatic containment to rapidly progressing tuberculosis (TB). The mechanisms controlling TB progression in immunologically-competent hosts remain unclear.To address these mechanisms, we analyzed...

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Main Authors: Irina V Lyadova, Evgeny N Tsiganov, Marina A Kapina, Galena S Shepelkova, Vasily V Sosunov, Tatiana V Radaeva, Konstantin B Majorov, Natalya S Shmitova, Henk-Jan van den Ham, Vitaly V Ganusov, Rob J De Boer, Rachael Racine, Gary M Winslow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2864263?pdf=render