Experience with oral mexiletine in primary erythromelalgia in children
Primary erythromelalgia is characterized by burning pain, redness, and warmth in the extremities. We present two cases of primary erythromelalgia both of whom presented with a history of several months of severe burning pain in both hands and feet. Both patients had received multiple pain medication...
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King Faisal Specialist Hospital and Research Centre
2009-01-01
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Series: | Annals of Saudi Medicine |
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doaj-309aeda9b3dc48aeb8cb7160407afc042020-11-24T22:50:02ZengKing Faisal Specialist Hospital and Research CentreAnnals of Saudi Medicine0256-49472009-01-01294316318Experience with oral mexiletine in primary erythromelalgia in childrenIqbal JaveedBhat MushtaqCharoo BashirSyed WajidSheikh MushtaqBhat ImtiyazPrimary erythromelalgia is characterized by burning pain, redness, and warmth in the extremities. We present two cases of primary erythromelalgia both of whom presented with a history of several months of severe burning pain in both hands and feet. Both patients had received multiple pain medications with no improvement in symptoms. Pain was relieved by putting affected parts in ice cold water, which resulted in immersion injury of the affected parts. Both patients stopped taking part in school and social activities. We tried oral mexiletine, a class Ib antiarrythmic agent, in view of its reported role in various chronic painful conditions. Dramatic improvement was observed with its use. Both patients improved after several weeks of use, and there were fewer soaking episodes. We observed no adverse effects with mexilitine therapy.http://www.saudiannals.net/article.asp?issn=0256-4947;year=2009;volume=29;issue=4;spage=316;epage=318;aulast=Iqbal |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Iqbal Javeed Bhat Mushtaq Charoo Bashir Syed Wajid Sheikh Mushtaq Bhat Imtiyaz |
spellingShingle |
Iqbal Javeed Bhat Mushtaq Charoo Bashir Syed Wajid Sheikh Mushtaq Bhat Imtiyaz Experience with oral mexiletine in primary erythromelalgia in children Annals of Saudi Medicine |
author_facet |
Iqbal Javeed Bhat Mushtaq Charoo Bashir Syed Wajid Sheikh Mushtaq Bhat Imtiyaz |
author_sort |
Iqbal Javeed |
title |
Experience with oral mexiletine in primary erythromelalgia in children |
title_short |
Experience with oral mexiletine in primary erythromelalgia in children |
title_full |
Experience with oral mexiletine in primary erythromelalgia in children |
title_fullStr |
Experience with oral mexiletine in primary erythromelalgia in children |
title_full_unstemmed |
Experience with oral mexiletine in primary erythromelalgia in children |
title_sort |
experience with oral mexiletine in primary erythromelalgia in children |
publisher |
King Faisal Specialist Hospital and Research Centre |
series |
Annals of Saudi Medicine |
issn |
0256-4947 |
publishDate |
2009-01-01 |
description |
Primary erythromelalgia is characterized by burning pain, redness, and warmth in the extremities. We present two cases of primary erythromelalgia both of whom presented with a history of several months of severe burning pain in both hands and feet. Both patients had received multiple pain medications with no improvement in symptoms. Pain was relieved by putting affected parts in ice cold water, which resulted in immersion injury of the affected parts. Both patients stopped taking part in school and social activities. We tried oral mexiletine, a class Ib antiarrythmic agent, in view of its reported role in various chronic painful conditions. Dramatic improvement was observed with its use. Both patients improved after several weeks of use, and there were fewer soaking episodes. We observed no adverse effects with mexilitine therapy. |
url |
http://www.saudiannals.net/article.asp?issn=0256-4947;year=2009;volume=29;issue=4;spage=316;epage=318;aulast=Iqbal |
work_keys_str_mv |
AT iqbaljaveed experiencewithoralmexiletineinprimaryerythromelalgiainchildren AT bhatmushtaq experiencewithoralmexiletineinprimaryerythromelalgiainchildren AT charoobashir experiencewithoralmexiletineinprimaryerythromelalgiainchildren AT syedwajid experiencewithoralmexiletineinprimaryerythromelalgiainchildren AT sheikhmushtaq experiencewithoralmexiletineinprimaryerythromelalgiainchildren AT bhatimtiyaz experiencewithoralmexiletineinprimaryerythromelalgiainchildren |
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