A Potential SARS-CoV-2 Variant of Interest (VOI) Harboring Mutation E484K in the Spike Protein Was Identified within Lineage B.1.1.33 Circulating in Brazil

A Potential SARS-CoV-2 Variant of Interest (VOI) Harboring Mutation E484K in the Spike Protein Was Identified within Lineage B.1.1.33 Circulating in Brazil

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Brazil was dominated by two lineages designated as B.1.1.28 and B.1.1.33. The two SARS-CoV-2 variants harboring mutations at the receptor-binding domain of the Spike (S) protein, designated as lineages P.1 and P.2, evolved...

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Bibliographic Details
Main Authors: Paola Cristina Resende, Tiago Gräf, Anna Carolina Dias Paixão, Luciana Appolinario, Renata Serrano Lopes, Ana Carolina da Fonseca Mendonça, Alice Sampaio Barreto da Rocha, Fernando Couto Motta, Lidio Gonçalves Lima Neto, Ricardo Khouri Cunha, Camila Indiani de Oliveira, Pedro Santos-Muccillo, João Felipe Bezerra, Dalane Loudal Florentino Teixeira, Irina Riediger, Maria do Carmo Debur, Rodrigo Ribeiro-Rodrigues, Anderson Brandao Leite, Cliomar Alves do Santos, Tatiana Schäffer Gregianini, Sandra Bianchini Fernandes, André Felipe Leal Bernardes, Andrea Cony Cavalcanti, Fábio Miyajima, Claudio Sachhi, Tirza Mattos, Cristiano Fernandes da Costa, Edson Delatorre, Gabriel L. Wallau, Felipe G. Naveca, Gonzalo Bello, Marilda Mendonça Siqueira
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
SARS-CoV-2
E484K
variant of Interest
genomic epidemiology
Brazil
Online Access:https://www.mdpi.com/1999-4915/13/5/724

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