LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate

Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1...

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Main Authors:	Run Jin, Samantha Klasfeld, Yang Zhu, Meilin Fernandez Garcia, Jun Xiao, Soon-Ki Han, Adam Konkol, Doris Wagner
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-01-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-20883-w

id	doaj-30ac2aa2b2134476b24948b7bf252727
record_format	Article
spelling	doaj-30ac2aa2b2134476b24948b7bf2527272021-01-31T12:20:26ZengNature Publishing GroupNature Communications2041-17232021-01-0112111410.1038/s41467-020-20883-wLEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fateRun Jin0Samantha Klasfeld1Yang Zhu2Meilin Fernandez Garcia3Jun Xiao4Soon-Ki Han5Adam Konkol6Doris Wagner7Biology Department, University of PennsylvaniaBiology Department, University of PennsylvaniaBiology Department, University of PennsylvaniaSchool of MedicineBiology Department, University of PennsylvaniaBiology Department, University of PennsylvaniaBiology Department, University of PennsylvaniaBiology Department, University of PennsylvaniaPioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1 and recruiting SWI/SNF chromatin remodelers.https://doi.org/10.1038/s41467-020-20883-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Run Jin Samantha Klasfeld Yang Zhu Meilin Fernandez Garcia Jun Xiao Soon-Ki Han Adam Konkol Doris Wagner
spellingShingle	Run Jin Samantha Klasfeld Yang Zhu Meilin Fernandez Garcia Jun Xiao Soon-Ki Han Adam Konkol Doris Wagner LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate Nature Communications
author_facet	Run Jin Samantha Klasfeld Yang Zhu Meilin Fernandez Garcia Jun Xiao Soon-Ki Han Adam Konkol Doris Wagner
author_sort	Run Jin
title	LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_short	LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_full	LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_fullStr	LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_full_unstemmed	LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_sort	leafy is a pioneer transcription factor and licenses cell reprogramming to floral fate
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-01-01
description	Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1 and recruiting SWI/SNF chromatin remodelers.
url	https://doi.org/10.1038/s41467-020-20883-w
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LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate

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