Five New Amicoumacins Isolated from a Marine-Derived Bacterium Bacillus subtilis

Five New Amicoumacins Isolated from a Marine-Derived Bacterium Bacillus subtilis

Four novel amicoumacins, namely lipoamicoumacins A–D (1–4), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR...

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Bibliographic Details
Main Authors: Wenhan Lin, Pei-Yuan Qian, Xixiang Zhang, Xiangrong Guo, Lingli Liu, Pok Yui Lai, Zhuang Han, Ying Xu, Yongxin Li
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Marine Drugs
Subjects:
antibacterial
cytotoxicity
lipoamicoumacin
Bacillus subtilis
Online Access:http://www.mdpi.com/1660-3397/10/2/319/
Description
Summary:Four novel amicoumacins, namely lipoamicoumacins A–D (1–4), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR, CD and MS) analysis and in comparison with data in literature.
ISSN:1660-3397

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