Rh(III)-catalyzed direct cross-dehydrogenative coupling of aromatic nitriles with heteroarenes: Rapid access to biheteroaryl-2-carbonitriles
Transition-metal-catalyzed direct C–H/C–H cross-coupling reactions as efficient and atom-economical approaches have been widely used to build up complex heterocyclic compounds. However, the strategy for preparation of biphenyl-2-carbonitriles has not been well established. Herein, we described the f...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co. Ltd.
2020-11-01
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| Series: | Green Synthesis and Catalysis |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666554920300284 |
| Summary: | Transition-metal-catalyzed direct C–H/C–H cross-coupling reactions as efficient and atom-economical approaches have been widely used to build up complex heterocyclic compounds. However, the strategy for preparation of biphenyl-2-carbonitriles has not been well established. Herein, we described the first cyanogen directed Rh(III)-catalyzed CDC reaction of aromatic nitriles with heteroarenes. Various biphenyl-2-carbonitrilederivatives were obtained with broad functional group compatibility. |
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| ISSN: | 2666-5549 |