Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis
The study was carried out on 1104 people of visceral leishmaniasis (VL) endemic region to detect the suitable marker in asymptomatic individuals that illustrate as a marker for conversion in symptomatic VL subject. In this study, 46 individuals (asymptomatic) with rK39 strip test positive without an...
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doaj-30e5ab2e49174aeb9c7e4d20b75ff6252020-11-24T21:49:12ZengDeccan College of Medical SciencesJournal of Medical and Allied Sciences2231-16962231-170X2019-07-0192969910.5455/jmas.5204152041Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasisRoshan Kamal Topno0Rajeev Kumar1Krishna Pandey2Manas Ranjan Dikhit3Major Madhukar4Maneesh Kumar5Sanjiva Bimal6Niyamat Ali Siddiqui7Vidyanand Ravi Das8Kanhaiya Agrawal9Neena Verma10Chandra Shekhar Lal11Pradeep Das12Department of Epidemiology, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Community Medicine, Nalanda Medical College & Hospital, Patna-800007, Bihar, India Department of Clinical Medicine, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Bioinformatics, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Clinical Medicine, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Virology, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Immunology, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Bio-Statistics, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Clinical Medicine, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Clinical Medicine, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Pathology, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Bio-Chemistry, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India Department of Molecular Biology, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, IndiaThe study was carried out on 1104 people of visceral leishmaniasis (VL) endemic region to detect the suitable marker in asymptomatic individuals that illustrate as a marker for conversion in symptomatic VL subject. In this study, 46 individuals (asymptomatic) with rK39 strip test positive without any previous VL sign and symptoms were later found symptomatic. Hematological and immunological investigations illustrated the lower hemoglobin (g/dl) and increase in interleukin-10 (IL-10) respectively from normal range which would be the primary markers in the asymptomatic individuals that might convert to symptomatic VL. [J Med Allied Sci 2019; 9(2.000): 96-99]http://www.ejmanager.com/fulltextpdf.php?mno=52041AsymptomaticHematological markerImmunological markerLeishmaniasis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Roshan Kamal Topno Rajeev Kumar Krishna Pandey Manas Ranjan Dikhit Major Madhukar Maneesh Kumar Sanjiva Bimal Niyamat Ali Siddiqui Vidyanand Ravi Das Kanhaiya Agrawal Neena Verma Chandra Shekhar Lal Pradeep Das |
spellingShingle |
Roshan Kamal Topno Rajeev Kumar Krishna Pandey Manas Ranjan Dikhit Major Madhukar Maneesh Kumar Sanjiva Bimal Niyamat Ali Siddiqui Vidyanand Ravi Das Kanhaiya Agrawal Neena Verma Chandra Shekhar Lal Pradeep Das Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis Journal of Medical and Allied Sciences Asymptomatic Hematological marker Immunological marker Leishmaniasis |
author_facet |
Roshan Kamal Topno Rajeev Kumar Krishna Pandey Manas Ranjan Dikhit Major Madhukar Maneesh Kumar Sanjiva Bimal Niyamat Ali Siddiqui Vidyanand Ravi Das Kanhaiya Agrawal Neena Verma Chandra Shekhar Lal Pradeep Das |
author_sort |
Roshan Kamal Topno |
title |
Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis |
title_short |
Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis |
title_full |
Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis |
title_fullStr |
Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis |
title_full_unstemmed |
Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis |
title_sort |
early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis |
publisher |
Deccan College of Medical Sciences |
series |
Journal of Medical and Allied Sciences |
issn |
2231-1696 2231-170X |
publishDate |
2019-07-01 |
description |
The study was carried out on 1104 people of visceral leishmaniasis (VL) endemic region to detect the suitable marker in asymptomatic individuals that illustrate as a marker for conversion in symptomatic VL subject. In this study, 46 individuals (asymptomatic) with rK39 strip test positive without any previous VL sign and symptoms were later found symptomatic. Hematological and immunological investigations illustrated the lower hemoglobin (g/dl) and increase in interleukin-10 (IL-10) respectively from normal range which would be the primary markers in the asymptomatic individuals that might convert to symptomatic VL. [J Med Allied Sci 2019; 9(2.000): 96-99] |
topic |
Asymptomatic Hematological marker Immunological marker Leishmaniasis |
url |
http://www.ejmanager.com/fulltextpdf.php?mno=52041 |
work_keys_str_mv |
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