A Deep Learning Framework for Identifying Zone I in RetCam Images
Retinopathy of prematurity (ROP) has been one of the worldwide causes of blindness among children. Grading and treatment guidelines of ROP are mainly based on zone, stage, and plus disease. For serious ROP, identifying zone is more important than staging. However, identifying zone I from RetCam fund...
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doaj-30f503df77fa40eebe1f9eb2c50260682021-04-05T17:16:48ZengIEEEIEEE Access2169-35362019-01-01710353010353710.1109/ACCESS.2019.29301208767920A Deep Learning Framework for Identifying Zone I in RetCam ImagesJinfeng Zhao0Baiying Lei1https://orcid.org/0000-0002-3087-2550Zhenquan Wu2Yinsheng Zhang3https://orcid.org/0000-0003-4971-8809Yafeng Li4Li Wang5Ruyin Tian6Yi Chen7Dahui Ma8Jiantao Wang9Tianfu Wang10Guozhen Chen11Jian Zeng12Guoming Zhang13Shenzhen Eye Hospital, Shenzhen, ChinaHealth Science Center, School of Biomedical Engineering, Shenzhen University, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaSchool of Management and E-Business, Zhejiang Gongshang University, Hangzhou, ChinaHangzhou Zhiquan Intelligence Technology Company Ltd., Hangzhou, ChinaHangzhou Zhiquan Intelligence Technology Company Ltd., Hangzhou, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaHealth Science Center, School of Biomedical Engineering, Shenzhen University, Shenzhen, ChinaHealth Science Center, School of Biomedical Engineering, Shenzhen University, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaRetinopathy of prematurity (ROP) has been one of the worldwide causes of blindness among children. Grading and treatment guidelines of ROP are mainly based on zone, stage, and plus disease. For serious ROP, identifying zone is more important than staging. However, identifying zone I from RetCam fundus images is not accurate and subjective by ophthalmologists. To address it, we develop a new deep learning framework to automatically identify zone I from RetCam images. Specifically, we train a deep convolutional neural network (DCNN) algorithm based on the RetCam images. The disc and macular center in terms of the threshold of intersection over union (IOU) were identified automatically. The algorithm is validated on fundus images and results show that zone I identification accuracy of 91% is achieved when the IOU threshold is 0.8. The obtained promising identification accuracy of zone I from the RetCam images indicates the potential applications in ROP grading, monitoring, and prognosis for infants.https://ieeexplore.ieee.org/document/8767920/Retinopathy of prematuritydeep convolutional neural networkoptic discmacular centerzone I |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jinfeng Zhao Baiying Lei Zhenquan Wu Yinsheng Zhang Yafeng Li Li Wang Ruyin Tian Yi Chen Dahui Ma Jiantao Wang Tianfu Wang Guozhen Chen Jian Zeng Guoming Zhang |
spellingShingle |
Jinfeng Zhao Baiying Lei Zhenquan Wu Yinsheng Zhang Yafeng Li Li Wang Ruyin Tian Yi Chen Dahui Ma Jiantao Wang Tianfu Wang Guozhen Chen Jian Zeng Guoming Zhang A Deep Learning Framework for Identifying Zone I in RetCam Images IEEE Access Retinopathy of prematurity deep convolutional neural network optic disc macular center zone I |
author_facet |
Jinfeng Zhao Baiying Lei Zhenquan Wu Yinsheng Zhang Yafeng Li Li Wang Ruyin Tian Yi Chen Dahui Ma Jiantao Wang Tianfu Wang Guozhen Chen Jian Zeng Guoming Zhang |
author_sort |
Jinfeng Zhao |
title |
A Deep Learning Framework for Identifying Zone I in RetCam Images |
title_short |
A Deep Learning Framework for Identifying Zone I in RetCam Images |
title_full |
A Deep Learning Framework for Identifying Zone I in RetCam Images |
title_fullStr |
A Deep Learning Framework for Identifying Zone I in RetCam Images |
title_full_unstemmed |
A Deep Learning Framework for Identifying Zone I in RetCam Images |
title_sort |
deep learning framework for identifying zone i in retcam images |
publisher |
IEEE |
series |
IEEE Access |
issn |
2169-3536 |
publishDate |
2019-01-01 |
description |
Retinopathy of prematurity (ROP) has been one of the worldwide causes of blindness among children. Grading and treatment guidelines of ROP are mainly based on zone, stage, and plus disease. For serious ROP, identifying zone is more important than staging. However, identifying zone I from RetCam fundus images is not accurate and subjective by ophthalmologists. To address it, we develop a new deep learning framework to automatically identify zone I from RetCam images. Specifically, we train a deep convolutional neural network (DCNN) algorithm based on the RetCam images. The disc and macular center in terms of the threshold of intersection over union (IOU) were identified automatically. The algorithm is validated on fundus images and results show that zone I identification accuracy of 91% is achieved when the IOU threshold is 0.8. The obtained promising identification accuracy of zone I from the RetCam images indicates the potential applications in ROP grading, monitoring, and prognosis for infants. |
topic |
Retinopathy of prematurity deep convolutional neural network optic disc macular center zone I |
url |
https://ieeexplore.ieee.org/document/8767920/ |
work_keys_str_mv |
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