A Deep Learning Framework for Identifying Zone I in RetCam Images

Retinopathy of prematurity (ROP) has been one of the worldwide causes of blindness among children. Grading and treatment guidelines of ROP are mainly based on zone, stage, and plus disease. For serious ROP, identifying zone is more important than staging. However, identifying zone I from RetCam fund...

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Main Authors: Jinfeng Zhao, Baiying Lei, Zhenquan Wu, Yinsheng Zhang, Yafeng Li, Li Wang, Ruyin Tian, Yi Chen, Dahui Ma, Jiantao Wang, Tianfu Wang, Guozhen Chen, Jian Zeng, Guoming Zhang
Format: Article
Language:English
Published: IEEE 2019-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/8767920/
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spelling doaj-30f503df77fa40eebe1f9eb2c50260682021-04-05T17:16:48ZengIEEEIEEE Access2169-35362019-01-01710353010353710.1109/ACCESS.2019.29301208767920A Deep Learning Framework for Identifying Zone I in RetCam ImagesJinfeng Zhao0Baiying Lei1https://orcid.org/0000-0002-3087-2550Zhenquan Wu2Yinsheng Zhang3https://orcid.org/0000-0003-4971-8809Yafeng Li4Li Wang5Ruyin Tian6Yi Chen7Dahui Ma8Jiantao Wang9Tianfu Wang10Guozhen Chen11Jian Zeng12Guoming Zhang13Shenzhen Eye Hospital, Shenzhen, ChinaHealth Science Center, School of Biomedical Engineering, Shenzhen University, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaSchool of Management and E-Business, Zhejiang Gongshang University, Hangzhou, ChinaHangzhou Zhiquan Intelligence Technology Company Ltd., Hangzhou, ChinaHangzhou Zhiquan Intelligence Technology Company Ltd., Hangzhou, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaHealth Science Center, School of Biomedical Engineering, Shenzhen University, Shenzhen, ChinaHealth Science Center, School of Biomedical Engineering, Shenzhen University, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaShenzhen Eye Hospital, Shenzhen, ChinaRetinopathy of prematurity (ROP) has been one of the worldwide causes of blindness among children. Grading and treatment guidelines of ROP are mainly based on zone, stage, and plus disease. For serious ROP, identifying zone is more important than staging. However, identifying zone I from RetCam fundus images is not accurate and subjective by ophthalmologists. To address it, we develop a new deep learning framework to automatically identify zone I from RetCam images. Specifically, we train a deep convolutional neural network (DCNN) algorithm based on the RetCam images. The disc and macular center in terms of the threshold of intersection over union (IOU) were identified automatically. The algorithm is validated on fundus images and results show that zone I identification accuracy of 91% is achieved when the IOU threshold is 0.8. The obtained promising identification accuracy of zone I from the RetCam images indicates the potential applications in ROP grading, monitoring, and prognosis for infants.https://ieeexplore.ieee.org/document/8767920/Retinopathy of prematuritydeep convolutional neural networkoptic discmacular centerzone I
collection DOAJ
language English
format Article
sources DOAJ
author Jinfeng Zhao
Baiying Lei
Zhenquan Wu
Yinsheng Zhang
Yafeng Li
Li Wang
Ruyin Tian
Yi Chen
Dahui Ma
Jiantao Wang
Tianfu Wang
Guozhen Chen
Jian Zeng
Guoming Zhang
spellingShingle Jinfeng Zhao
Baiying Lei
Zhenquan Wu
Yinsheng Zhang
Yafeng Li
Li Wang
Ruyin Tian
Yi Chen
Dahui Ma
Jiantao Wang
Tianfu Wang
Guozhen Chen
Jian Zeng
Guoming Zhang
A Deep Learning Framework for Identifying Zone I in RetCam Images
IEEE Access
Retinopathy of prematurity
deep convolutional neural network
optic disc
macular center
zone I
author_facet Jinfeng Zhao
Baiying Lei
Zhenquan Wu
Yinsheng Zhang
Yafeng Li
Li Wang
Ruyin Tian
Yi Chen
Dahui Ma
Jiantao Wang
Tianfu Wang
Guozhen Chen
Jian Zeng
Guoming Zhang
author_sort Jinfeng Zhao
title A Deep Learning Framework for Identifying Zone I in RetCam Images
title_short A Deep Learning Framework for Identifying Zone I in RetCam Images
title_full A Deep Learning Framework for Identifying Zone I in RetCam Images
title_fullStr A Deep Learning Framework for Identifying Zone I in RetCam Images
title_full_unstemmed A Deep Learning Framework for Identifying Zone I in RetCam Images
title_sort deep learning framework for identifying zone i in retcam images
publisher IEEE
series IEEE Access
issn 2169-3536
publishDate 2019-01-01
description Retinopathy of prematurity (ROP) has been one of the worldwide causes of blindness among children. Grading and treatment guidelines of ROP are mainly based on zone, stage, and plus disease. For serious ROP, identifying zone is more important than staging. However, identifying zone I from RetCam fundus images is not accurate and subjective by ophthalmologists. To address it, we develop a new deep learning framework to automatically identify zone I from RetCam images. Specifically, we train a deep convolutional neural network (DCNN) algorithm based on the RetCam images. The disc and macular center in terms of the threshold of intersection over union (IOU) were identified automatically. The algorithm is validated on fundus images and results show that zone I identification accuracy of 91% is achieved when the IOU threshold is 0.8. The obtained promising identification accuracy of zone I from the RetCam images indicates the potential applications in ROP grading, monitoring, and prognosis for infants.
topic Retinopathy of prematurity
deep convolutional neural network
optic disc
macular center
zone I
url https://ieeexplore.ieee.org/document/8767920/
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