Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat

Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat

Objective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression.  In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac t...

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Main Authors: Danka Đevenica, Anita Markotić, Nikolina Režić-Mužinić, Igor Jelaska, Tatijana Zemunik, Hrvoje Delić, Vedrana Čikeš Čulić
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
CD15s(sialyl Lexis X antigen)
CD77(globotriaosylceramide)
CD34 antigen
Environment
Online Access:http://ijbms.mums.ac.ir/article_7462_a245c794b6940b8b4a8333dd5a6c7879.pdf
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spelling doaj-30f8375f6baa46cc82cfb8ec575b059a2020-11-24T21:04:11ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences 2008-38662008-38742016-08-0119882182810.22038/ijbms.2016.74627462Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in ratDanka Đevenica0Anita Markotić1Nikolina Režić-Mužinić2Igor Jelaska3Tatijana Zemunik4Hrvoje Delić5Vedrana Čikeš Čulić6Postgraduate Student at University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaFaculty of Kinesiology, University of Split, Split, CroatiaDepartment of Medical Biology, University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaObjective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression.  In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Materials and Methods:Expression of CD11b and CD15s on leukocytes, as well as CD77 and CD34 expression on endothelial cells in cell suspensions of renal, pulmonary and cardiac tissue in rats after hyperbaric treatment and in control rats were determined by flow cytometry. Results: Hyperbaric treatment significantly increased percentage of leukocytes expressing CD15s+CD11b- (from 1.71±1.11 to 23.42±2.85, Phttp://ijbms.mums.ac.ir/article_7462_a245c794b6940b8b4a8333dd5a6c7879.pdfCD15s(sialyl Lexis X antigen)CD77(globotriaosylceramide)CD34 antigenEnvironment
collection DOAJ
language English
format Article
sources DOAJ
author Danka Đevenica
Anita Markotić
Nikolina Režić-Mužinić
Igor Jelaska
Tatijana Zemunik
Hrvoje Delić
Vedrana Čikeš Čulić
spellingShingle Danka Đevenica
Anita Markotić
Nikolina Režić-Mužinić
Igor Jelaska
Tatijana Zemunik
Hrvoje Delić
Vedrana Čikeš Čulić
Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
Iranian Journal of Basic Medical Sciences
CD15s(sialyl Lexis X antigen)
CD77(globotriaosylceramide)
CD34 antigen
Environment
author_facet Danka Đevenica
Anita Markotić
Nikolina Režić-Mužinić
Igor Jelaska
Tatijana Zemunik
Hrvoje Delić
Vedrana Čikeš Čulić
author_sort Danka Đevenica
title Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
title_short Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
title_full Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
title_fullStr Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
title_full_unstemmed Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
title_sort hyperbaric environment up-regulates cd15s expression on leukocytes, down-regulates cd77 expression on renal cells and up-regulates cd34 expression on pulmonary and cardiac cells in rat
publisher Mashhad University of Medical Sciences
series Iranian Journal of Basic Medical Sciences
issn 2008-3866
2008-3874
publishDate 2016-08-01
description Objective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression.  In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Materials and Methods:Expression of CD11b and CD15s on leukocytes, as well as CD77 and CD34 expression on endothelial cells in cell suspensions of renal, pulmonary and cardiac tissue in rats after hyperbaric treatment and in control rats were determined by flow cytometry. Results: Hyperbaric treatment significantly increased percentage of leukocytes expressing CD15s+CD11b- (from 1.71±1.11 to 23.42±2.85, P
topic CD15s(sialyl Lexis X antigen)
CD77(globotriaosylceramide)
CD34 antigen
Environment
url http://ijbms.mums.ac.ir/article_7462_a245c794b6940b8b4a8333dd5a6c7879.pdf
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