Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus
The relationship between gene expression and morphology to classify PV interneurons is unclear. Here, the authors show transcriptional continuity of morphologically distinct mouse hippocampal PV interneurons subtypes, combining single-cell RNA sequencing and electrophysiology.
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Nature Publishing Group
2021-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-20328-4 |
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doaj-30fe6870647e4bc89e435480fcc57e662021-01-10T12:18:59ZengNature Publishing GroupNature Communications2041-17232021-01-0112111510.1038/s41467-020-20328-4Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampusLin Que0David Lukacsovich1Wenshu Luo2Csaba Földy3Laboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of ZürichLaboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of ZürichLaboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of ZürichLaboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of ZürichThe relationship between gene expression and morphology to classify PV interneurons is unclear. Here, the authors show transcriptional continuity of morphologically distinct mouse hippocampal PV interneurons subtypes, combining single-cell RNA sequencing and electrophysiology.https://doi.org/10.1038/s41467-020-20328-4 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lin Que David Lukacsovich Wenshu Luo Csaba Földy |
spellingShingle |
Lin Que David Lukacsovich Wenshu Luo Csaba Földy Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus Nature Communications |
author_facet |
Lin Que David Lukacsovich Wenshu Luo Csaba Földy |
author_sort |
Lin Que |
title |
Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus |
title_short |
Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus |
title_full |
Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus |
title_fullStr |
Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus |
title_full_unstemmed |
Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus |
title_sort |
transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2021-01-01 |
description |
The relationship between gene expression and morphology to classify PV interneurons is unclear. Here, the authors show transcriptional continuity of morphologically distinct mouse hippocampal PV interneurons subtypes, combining single-cell RNA sequencing and electrophysiology. |
url |
https://doi.org/10.1038/s41467-020-20328-4 |
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