Role of Exercise-induced Adiponectin Activation on Obese and Diabetic Individuals

• Main Authors: Kangil Lim, Kijeong Kim
• Format: Article
• Language: Korean
• Published: The Korean Society of Exercise Physiology 2020-08-01
• Series: 운동과학
• Subjects: exercise; adiponectin; obesity; diabetes
• Online Access: http://www.ksep-es.org/upload/pdf/es-29-3-208.pdf

PURPOSE The physiological role of adipocytokines on obesity, diabetes, and insulin resistance is not clearly understood yet. Furthermore, the mechanism of exercise-induced changes in plasma adiponectin in obesity and diabetes is not known well. The aim of this review is to describe the role of exercise on the adiponectin production in adipose tissue of the obesity and diabetes. METHODS This study reviews 46 previous studies focusing on the effect of exercise on adiponectin in obese and diabetic individuals. RESULTS Increasing adiponectin levels after long-term exercise training in obese and diabetic individuals have inconsistent support in the scientific literature. However, the present review summarized evidence that supports for exercise training as a viable strategy to increase adiponectin in obese and diabetic individuals. CONCLUSIONS Despite the importance of regular physical activity for the prevention of obesity and diabetes outlined in numerous guidelines and recommendations, previous studies showed inconsistent results regarding the effect of physical activity among obese and diabetic individuals. This review suggested that exercise training induces the augmentation of the anti-inflammatory cytokine adiponectin and in turn, it provides long-term health outcomes for obese and diabetic individuals.