Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model
The effectiveness of water decoction of Tagetes patula was studied against the chronic nonbacterial prostatitis in a rat model induced by estradiol subcuta-neously in a castrated male rat. The low-dose decoction of T. patula significantly ameliorated the prostatitis. The low-dose of polysaccharide...
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Bangladesh Pharmacological Society
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doaj-311c9de2c70041aa83834e72bd288f1e2020-11-25T00:39:02ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882017-10-0112410.3329/bjp.v12i4.3324022026Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat modelXueying Liu0Xiaoku Ran1Deqiang Dou2Decheng Cai3College of Pharmacy, Liaoning University of Traditional Chinese Medicine, DalianCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, DalianCollege of Pharmacy, Liaoning University of Traditional Chinese Medicine, DalianDalian Wuzhou Holy Herb Scientific and Technological Co. Ltd, DalianThe effectiveness of water decoction of Tagetes patula was studied against the chronic nonbacterial prostatitis in a rat model induced by estradiol subcuta-neously in a castrated male rat. The low-dose decoction of T. patula significantly ameliorated the prostatitis. The low-dose of polysaccharide and supernatant constituent of T. patula decreased the levels of IL-1?, TNF-?, PSA, and EGF, and improved the levels of testosterone and dihydrotestosterone in vivo. Further, the chemical study indicated that flavonoids were predominant in the supernatant constituent of T. patula. The flavonoids and polysaccha-rides were the effective constituents against prostatitis and this effect may be mediated by keeping hormone balance and a down-regulation of the in?ammatory mediator level of the prostate. Video Clip of Methodology: 9 min 43 Sec Full Screen Alternate https://www.banglajol.info/index.php/BJP/article/view/33240Chronic nonbacterial prostatitisCytokinesProstatitisTagetes patula L.Traditional Chinese medicine |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xueying Liu Xiaoku Ran Deqiang Dou Decheng Cai |
spellingShingle |
Xueying Liu Xiaoku Ran Deqiang Dou Decheng Cai Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model Bangladesh Journal of Pharmacology Chronic nonbacterial prostatitis Cytokines Prostatitis Tagetes patula L. Traditional Chinese medicine |
author_facet |
Xueying Liu Xiaoku Ran Deqiang Dou Decheng Cai |
author_sort |
Xueying Liu |
title |
Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model |
title_short |
Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model |
title_full |
Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model |
title_fullStr |
Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model |
title_full_unstemmed |
Effectiveness of Tagetes patula against chronic nonbacterial prostatitis in rat model |
title_sort |
effectiveness of tagetes patula against chronic nonbacterial prostatitis in rat model |
publisher |
Bangladesh Pharmacological Society |
series |
Bangladesh Journal of Pharmacology |
issn |
1991-0088 |
publishDate |
2017-10-01 |
description |
The effectiveness of water decoction of Tagetes patula was studied against the chronic nonbacterial prostatitis in a rat model induced by estradiol subcuta-neously in a castrated male rat. The low-dose decoction of T. patula significantly ameliorated the prostatitis. The low-dose of polysaccharide and supernatant constituent of T. patula decreased the levels of IL-1?, TNF-?, PSA, and EGF, and improved the levels of testosterone and dihydrotestosterone in vivo. Further, the chemical study indicated that flavonoids were predominant in the supernatant constituent of T. patula. The flavonoids and polysaccha-rides were the effective constituents against prostatitis and this effect may be mediated by keeping hormone balance and a down-regulation of the in?ammatory mediator level of the prostate.
Video Clip of Methodology:
9 min 43 Sec Full Screen Alternate
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topic |
Chronic nonbacterial prostatitis Cytokines Prostatitis Tagetes patula L. Traditional Chinese medicine |
url |
https://www.banglajol.info/index.php/BJP/article/view/33240 |
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