Targeting Nrf2/HO-1 anti-oxidant signaling pathway in the progression of multiple sclerosis and influences on neurological dysfunctions
The nuclear factor erythroid 2-related factor (Nrf2) transcription factor/Hemoxygenase 1 (HO-1) is a primary regulator of essential cytoprotective responses in the brain. It activates the expression of various neuroprotective genes that code for anti-oxidant, anti-inflammatory, and detoxifying prote...
Main Authors: | Shubham Upadhayay, Sidharth Mehan, Ph.D, M.Pharm |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | Brain Disorders |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666459321000184 |
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