T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative marker.
BACKGROUND: Regulatory T-cells (Tregs), characterized as CD4+CD25(hi) T-cells expressing FOXP3, play a crucial role in controlling healthy immune development during early immune maturation. Recently, FOXP3 demethylation was suggested to be a novel marker for natural Tregs in adults. In cord blood, t...
Main Authors: | Jing Liu, Anna Lluis, Sabina Illi, Laura Layland, Sven Olek, Erika von Mutius, Bianca Schaub |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2953505?pdf=render |
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