A Review of Newly Diagnosed Glioblastoma

A Review of Newly Diagnosed Glioblastoma

Glioblastoma is an aggressive and inevitably recurrent primary intra-axial brain tumor with a dismal prognosis. The current mainstay of treatment involves maximally safe surgical resection followed by radiotherapy over a 6-week period with concomitant temozolomide chemotherapy followed by temozolomi...

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Bibliographic Details
Main Authors: Bryan Oronsky, Tony R. Reid, Arnold Oronsky, Navjot Sandhu, Susan J. Knox
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
radiation therapy
high-grade gliomas
cancer
brain tumors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.574012/full
Description
Summary:Glioblastoma is an aggressive and inevitably recurrent primary intra-axial brain tumor with a dismal prognosis. The current mainstay of treatment involves maximally safe surgical resection followed by radiotherapy over a 6-week period with concomitant temozolomide chemotherapy followed by temozolomide maintenance. This review provides a summary of the epidemiological, clinical, histologic and genetic characteristics of newly diagnosed disease as well as the current standard of care and potential future therapeutic prospects.
ISSN:2234-943X

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