Contributions of IFN-γ and granulysin to the clearance of Plasmodium yoelii blood stage.
P. vivax-infected Retics (iRetics) express human leukocyte antigen class I (HLA-I), are recognized by CD8+ T cells and killed by granulysin (GNLY) and granzymes. However, how Plasmodium infection induces MHC-I expression on Retics is unknown. In addition, whether GNLY helps control Plasmodium infect...
Main Authors: | Natália Satchiko Hojo-Souza, Patrick Orestes de Azevedo, Júlia Teixeira de Castro, Andréa Teixeira-Carvalho, Judy Lieberman, Caroline Junqueira, Ricardo Tostes Gazzinelli |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-09-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008840 |
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