Antioxidant and Neuroprotective Effects of N-((3,4-Dihydro-2H-benzo[h]chromen-2-yl)methyl)-4-methoxyaniline in Primary Cultured Rat Cortical Cells: Involvement of ERK-CREB Signaling

Antioxidant and Neuroprotective Effects of N-((3,4-Dihydro-2H-benzo[h]chromen-2-yl)methyl)-4-methoxyaniline in Primary Cultured Rat Cortical Cells: Involvement of ERK-CREB Signaling

Excitotoxicity and oxidative stress play vital roles in the development of neurodegenerative disorders including Alzheimer’s disease (AD). In the present study, we investigated the effect of N-((3,4-dihydro-2H-benzo[h]chromen-2-yl)methyl)-4-methoxyaniline (BL-M) on excitotoxic neuronal cell damage i...

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Bibliographic Details
Main Authors: Kyeongjun Lee, Chowee Park, Yeonsoo Oh, Heesoon Lee, Jungsook Cho
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
Alzheimer’s disease
chromene derivative
excitotoxicity
ERK1/2
CREB phosphorylation
antioxidant
Online Access:http://www.mdpi.com/1420-3049/23/3/669

Internet

http://www.mdpi.com/1420-3049/23/3/669

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