Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus

Abstract Doublecortin X (DCX), known to be essential for neuronal migration and cortical layering in the developing brain, is a 40 kDa microtubule (MT)-associated protein. DCX directly interacts with MTs via its two structured doublecortin (DC) domains, but the dynamics of this association and the p...

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Bibliographic Details
Main Authors: Maryam Moslehi, Dominic C. H. Ng, Marie A. Bogoyevitch
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05340-x