Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus
Abstract Doublecortin X (DCX), known to be essential for neuronal migration and cortical layering in the developing brain, is a 40 kDa microtubule (MT)-associated protein. DCX directly interacts with MTs via its two structured doublecortin (DC) domains, but the dynamics of this association and the p...
Main Authors: | Maryam Moslehi, Dominic C. H. Ng, Marie A. Bogoyevitch |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-05340-x |
Similar Items
-
The evolving doublecortin (DCX) superfamily
by: Sapir Tamar, et al.
Published: (2006-07-01) -
Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides
by: Marissa E Maheu, et al.
Published: (2015-06-01) -
Doublecortin (DCX) is not essential for survival and differentiation of newborn neurons in the adult mouse dentate gyrus
by: Jagroop eDhaliwal, et al.
Published: (2016-01-01) -
Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice.
by: Friederike Klempin, et al.
Published: (2011-01-01) -
LIS1 and DCX: Implications for Brain Development and Human Disease in Relation to Microtubules
by: Orly Reiner
Published: (2013-01-01)