Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude

Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude

Background: Prolonged exposure to altitude-associated chronic hypoxia (CH) may cause high-altitude pulmonary hypertension (HAPH). Chronic intermittent hypobaric hypoxia (CIH) occurs in individuals who commute between sea level and high altitude. CIH is associated with repetitive acute hypoxic acclim...

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Bibliographic Details
Main Authors: Patricia Siques, Julio Brito, Edzard Schwedhelm, Eduardo Pena, Fabiola León-Velarde, Juan José De La Cruz, Rainer H. Böger, Juliane Hannemann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Physiology
Subjects:
ADMA
SDMA
nitric oxide
hypobaric hypoxia
right ventricle
endothelium
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00651/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00651/full

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