| Summary: | Diabetic nephropathy is a progredient disease which leads to the end stage renal disease and stands for a leading cause of its development in western countries. About one third of patients included in the dialysis program or transplanation program in the USA are diabetics. The aim of the paper was to analyze the degree of renal failure in diabetics by measuring the glomerular filtration rate (GFR) and to show the advantages of this method comparing with serum creatinine levels. Total numbers of 23 patients with diabetes mellitus type 1 or type 2 were anlyzed and controlled monthly during 6 months. Average GFR in the examined patients was 53,23±15,48 mL/min/1.73m2. Obtained values for GFR according to CKD Care and ESRD recommendations showed that the great number of diabetics had stage 3 renal failure while stages 1 and 5 were not registered. GFR is an important marker for diagnostics and estimation of renal failure progression in diabetics. Bearing in mind this facts, periodical controls in diabetics must be suplemented by measuring GFR, so as to perform early identification and determination of severity of renal failure. Measuring of lipoprotein levels and determination of glycemic profile must be done according to the National recommendations twice a year. Besides adequate glycoregulation, diabetics need statins therapy and antyhipertensive tratment with ACE inhibitors.
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