NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis

NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis

Background: Paracellular barriers play an important role in the pathogenesis of Inflammatory bowel disease (IBD) and maintain gut homeostasis. N-myc downstream-regulated gene 2 (NDRG2) has been reported to be a tumour suppressor gene and to inhibit colorectal cancer metastasis. However, whether NDRG...

Full description

Bibliographic Details
Main Authors: Mengying Wei, Yongzheng Ma, Liangliang Shen, Yuqiao Xu, Lijun Liu, Xin Bu, Zhihao Guo, Hongyan Qin, Zengshan Li, Zhe Wang, Kaichun Wu, Libo Yao, Jipeng Li, Jian Zhang
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:EBioMedicine
Subjects:
Colitis
NDRG2
Adherens junction
Colitis-associated colorectal cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304448

Internet

http://www.sciencedirect.com/science/article/pii/S2352396420304448

Similar Items