Mapping Cellular Microenvironments: Proximity Labeling and Complexome Profiling (Seventh Symposium of the Göttingen Proteomics Forum)

• Main Authors: Oliver Valerius, Abdul R. Asif, Tim Beißbarth, Rainer Bohrer, Hassan Dihazi, Kirstin Feussner, Olaf Jahn, Andrzej Majcherczyk, Bernhard Schmidt, Kerstin Schmitt, Henning Urlaub, Christof Lenz
• Format: Article
• Language: English
• Published: MDPI AG 2019-10-01
• Series: Cells
• Subjects: proteomics; complexome profiling; proximity labeling; mass spectrometry
• Online Access: https://www.mdpi.com/2073-4409/8/10/1192

Mass spectrometry-based proteomics methods are finding increasing use in structural biology research. Beyond simple interaction networks, information about stable protein-protein complexes or spatially proximal proteins helps to elucidate the biological functions of proteins in a wider cellular context. To shed light on new developments in this field, the Göttingen Proteomics Forum organized a one-day symposium focused on complexome profiling and proximity labeling, two emerging technologies that are gaining significant attention in biomolecular research. The symposium was held in Göttingen, Germany on 23 May, 2019, as part of a series of regular symposia organized by the Göttingen Proteomics Forum.