Identification of MupP as a New Peptidoglycan Recycling Factor and Antibiotic Resistance Determinant in Pseudomonas aeruginosa

Peptidoglycan (PG) is an essential cross-linked polymer that surrounds most bacterial cells to prevent osmotic rupture of the cytoplasmic membrane. Its synthesis relies on penicillin-binding proteins, the targets of beta-lactam antibiotics. Many Gram-negative bacteria, including the opportunistic pa...

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Bibliographic Details
Main Authors: Coralie Fumeaux, Thomas G. Bernhardt, Howard A. Shuman
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e00102-17

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