Identification of MupP as a New Peptidoglycan Recycling Factor and Antibiotic Resistance Determinant in Pseudomonas aeruginosa
Peptidoglycan (PG) is an essential cross-linked polymer that surrounds most bacterial cells to prevent osmotic rupture of the cytoplasmic membrane. Its synthesis relies on penicillin-binding proteins, the targets of beta-lactam antibiotics. Many Gram-negative bacteria, including the opportunistic pa...
Main Authors: | Coralie Fumeaux, Thomas G. Bernhardt, Howard A. Shuman |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-03-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/2/e00102-17 |
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