Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Report
Thyrotoxicosis and primary hyperaldosteronism both cause hypokalemic periodic paralysis. Here we report a 51-year-old woman presenting with severe hypokalemia due to both thyrotoxicosis and primary hyperaldosteronism. At first presentation, she had a potassium level of 1.5 mEq/L and thyrotoxicosis d...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Turkiye Klinikleri
2009-12-01
|
Series: | Turkish Journal of Endocrinology and Metabolism |
Subjects: | |
Online Access: | http://www.turkjem.org/eng/yazilar.asp?yaziid=620&sayiid=60 |
id |
doaj-31b86ecd73f34af387469a0f21091e97 |
---|---|
record_format |
Article |
spelling |
doaj-31b86ecd73f34af387469a0f21091e972020-11-25T02:28:20ZengTurkiye KlinikleriTurkish Journal of Endocrinology and Metabolism1301-21932009-12-011348790Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Reportİnan AnaforoğluAlimdar ŞimşekEkrem AlgünThyrotoxicosis and primary hyperaldosteronism both cause hypokalemic periodic paralysis. Here we report a 51-year-old woman presenting with severe hypokalemia due to both thyrotoxicosis and primary hyperaldosteronism. At first presentation, she had a potassium level of 1.5 mEq/L and thyrotoxicosis due to a hot nodule, and was diagnosed as having thyrotoxic hypokalemic periodic paralysis. After treatment with propylthiouracil and potassium, she completely regained muscle strength. Nevertheless, a decrease in potassium level was observed again when the replacement of potassium was discontinued. The further diagnostic work-up of the patient, who had also history of hypertention, revealed primary hyperaldosteronism and subclinical Cushing’s syndrome due to adrenal adenoma on the left side. Whether thyrotoxicosis contributed to the hypokalemic periodic paralysis in this patient is a matter of debate. Adrenal hyperfunction should be considered in all patients with hypertension and hypokalemia regardless of the presentation of the case. Turk Jem 2009; 13: 87-90http://www.turkjem.org/eng/yazilar.asp?yaziid=620&sayiid=60Hypokalemic periodic paralysisthyrotoxicosishyperaldosteronismSubclinical Cushing’s syndrome |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
İnan Anaforoğlu Alimdar Şimşek Ekrem Algün |
spellingShingle |
İnan Anaforoğlu Alimdar Şimşek Ekrem Algün Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Report Turkish Journal of Endocrinology and Metabolism Hypokalemic periodic paralysis thyrotoxicosis hyperaldosteronism Subclinical Cushing’s syndrome |
author_facet |
İnan Anaforoğlu Alimdar Şimşek Ekrem Algün |
author_sort |
İnan Anaforoğlu |
title |
Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Report |
title_short |
Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Report |
title_full |
Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Report |
title_fullStr |
Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Report |
title_full_unstemmed |
Conn’s Syndrome, Subclinical Cushing’s Syndrome and Thyrotoxicosis Presenting as Hypokalemic Periodic Paralysis: A Case Report |
title_sort |
conn’s syndrome, subclinical cushing’s syndrome and thyrotoxicosis presenting as hypokalemic periodic paralysis: a case report |
publisher |
Turkiye Klinikleri |
series |
Turkish Journal of Endocrinology and Metabolism |
issn |
1301-2193 |
publishDate |
2009-12-01 |
description |
Thyrotoxicosis and primary hyperaldosteronism both cause hypokalemic periodic paralysis. Here we report a 51-year-old woman presenting with severe hypokalemia due to both thyrotoxicosis and primary hyperaldosteronism. At first presentation, she had a potassium level of 1.5 mEq/L and thyrotoxicosis due to a hot nodule, and was diagnosed as having thyrotoxic hypokalemic periodic paralysis. After treatment with propylthiouracil and potassium, she completely regained muscle strength. Nevertheless, a decrease in potassium level was observed again when the replacement of potassium was discontinued. The further diagnostic work-up of the patient, who had also history of hypertention, revealed primary hyperaldosteronism and subclinical Cushing’s syndrome due to adrenal adenoma on the left side. Whether thyrotoxicosis contributed to the hypokalemic periodic paralysis in this patient is a matter of debate. Adrenal hyperfunction should be considered in all patients with hypertension and hypokalemia regardless of the presentation of the case. Turk Jem 2009; 13: 87-90 |
topic |
Hypokalemic periodic paralysis thyrotoxicosis hyperaldosteronism Subclinical Cushing’s syndrome |
url |
http://www.turkjem.org/eng/yazilar.asp?yaziid=620&sayiid=60 |
work_keys_str_mv |
AT inananaforoglu connssyndromesubclinicalcushingssyndromeandthyrotoxicosispresentingashypokalemicperiodicparalysisacasereport AT alimdarsimsek connssyndromesubclinicalcushingssyndromeandthyrotoxicosispresentingashypokalemicperiodicparalysisacasereport AT ekremalgun connssyndromesubclinicalcushingssyndromeandthyrotoxicosispresentingashypokalemicperiodicparalysisacasereport |
_version_ |
1724838858117349376 |