Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex

Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex

We investigated the role of full-length Drosophila Bicaudal D (BicD) binding partners in dynein-dynactin activation for mRNA transport on microtubules. Full-length BicD robustly activated dynein-dynactin motility only when both the mRNA binding protein Egalitarian (Egl) and K10 mRNA cargo were prese...

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Bibliographic Details
Main Authors: Thomas E Sladewski, Neil Billington, M Yusuf Ali, Carol S Bookwalter, Hailong Lu, Elena B Krementsova, Trina A Schroer, Kathleen M Trybus
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
mRNA transport
dynein
BicD
dynactin
Egalitarian
Online Access:https://elifesciences.org/articles/36306

Internet

https://elifesciences.org/articles/36306

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